ZFIN ID: ZDB-GENE-040108-1
Gene Name: cholinergic receptor nicotinic beta 3 subunit a
Gene Symbol: chrnb3a    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to contribute to acetylcholine binding activity and acetylcholine receptor activity. Predicted to be involved in several processes, including chemical synaptic transmission; regulation of membrane potential; and response to nicotine. Predicted to localize to acetylcholine-gated channel complex; neuron projection; and synapse.
Genome Resources: Alliance (1),  Gene:794401 (1),  Ensembl(GRCz11):ENSDARG00000052764 (2)
GENE EXPRESSION
All Expression Data: text only from Zirger et al., 2003
Wild-type Stages, Structures: Cleavage:64-cell (2.0h-2.25h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa12587 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39605 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • zko424a Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-chrnb3a 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH chrnb3a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH chrnb3a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process ion transmembrane transport (more)
    Cellular Component cell junction (more)
    Molecular Function acetylcholine-gated cation-selective channel activity (more)
    GO Terms (all 22)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA chrnb3a-201 (1)    Ensembl 2128
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM chrnb3a No data available
    MARKER RELATIONSHIPS
    chrnb3a Contained in: [BAC] CH73-380N15 (1), DKEY-234D14 (1) (order this)
    chrnb3a Contains: [STS] chunp6849 (1)
    chrnb3a Encodes: [cDNA] MGC:193626 (1), MGC:193636 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_201220 (1) 2163 nt
    Genomic GenBank:CT573161 (1) 102140 nt
    Select Tool
    Polypeptide UniProtKB:F1QKS3 (1) 467 aa
    Sequence Information (all 16)
    ORTHOLOGY for chrnb3a ( Chr: 1 )
    CITATIONS (26)