ZFIN ID: ZDB-GENE-031217-3
Gene Name: gap junction protein, alpha 3
Gene Symbol: gja3
Sequence Ontology ID : SO:0000704

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: Cx44 (1), cx46 (2), cx48.5 (1), dco (1), dococ (1), unm s215, unm s226

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 9 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits gap junction hemi-channel activity; involved in several processes, including animal organ development, cell communication by electrical coupling, and regulation of heart contraction;  ...
GENE EXPRESSION
All Expression Data: 5 figures from 5 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
s215 Unknown Unknown Unknown ENU
s226 Point Mutation Unknown Unknown ENU
Targeting reagents:
PHENOTYPE
Data: 7 figures from 3 publications
Observed in:
DISEASE ASSOCIATED WITH gja3 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
cataract 14 multiple types Cataract 14, multiple types 601885
DISEASE ASSOCIATED WITH gja3 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process cardiac conduction system development (more)
Cellular Component integral component of plasma membrane (more)
Molecular Function gap junction hemi-channel activity (more)
GO Terms (all 16)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000500 (1)
  • InterPro:IPR002262 (1)
  • InterPro:IPR013092 (1)
  • InterPro:IPR017990 (1)
  • InterPro:IPR019570 (1)
  • InterPro:IPR031862 (1)
  • InterPro:IPR034634 (1)
  • InterPro:IPR038359 (1)
  • PROSITE:PS00407 (1)
  • PROSITE:PS00408 (1)
  • Pfam:PF00029 (1)
  • Pfam:PF16791 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA gja3-001 (1) 1480
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM gja3
    MARKER RELATIONSHIPS
    gja3Contained in: [BAC] DKEY-51D17 (1) (order this)
    gja3Encodes: [cDNA] MGC:195070 (1) (order this), MGC:195085 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_207642 (1) 1305bp
    Genomic GenBank:CR392366 (1) 125898bp
    Select Tool
    Polypeptide UniProtKB:Q8JFD2 (1) 434aa
    Sequence Clusters UniGene:159333 (1)
    Sequence Information (all 35)
    OTHER gja3 GENE PAGES
  • Alliance (1)
  • Gene:387533 (1)
  • VEGA:OTTDARG00000020503 (1)
  • ORTHOLOGY for gja3 (Chr: 9)
    CITATIONS (35)