ZFIN ID: ZDB-GENE-031212-1
Gene Name: glypican 3
Gene Symbol: gpc3

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(Including Attributions)
Location: Chr: 14 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 4 figures from 2 publications
Wild-type Stages, Structures: Cleavage:8-cell (1.25h-1.5h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
  intestine, liver, midbrain, whole organism
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la018952Tg Transgenic Insertion Unknown Unknown DNA
la018953Tg Transgenic Insertion Unknown Unknown DNA
la018954Tg Transgenic Insertion Unknown Unknown DNA
la018955Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la018956Tg Transgenic Insertion Unknown Unknown DNA
    sa42411 Point Mutation Unknown Premature Stop ENU
    Targeting reagents: MO1-gpc3 (1)
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH gpc3 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    nephroblastoma Wilms tumor, somatic 194070
    Simpson-Golabi-Behmel syndrome Simpson-Golabi-Behmel syndrome, type 1 312870
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process negative regulation of canonical Wnt signaling pathway (more)
    Cellular Component anchored component of membrane (more)
    Molecular Function heparan sulfate proteoglycan binding (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001863 (1)
  • InterPro:IPR015501 (1)
  • Pfam:PF01153 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA gpc3-001 (1) 2558
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM gpc3 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    gpc3Contained in: [BAC] CH211-113B2 (1) (order this), DKEY-57B1 (1) (order this), DKEY-100E19 (1) (order this), DKEY-204C2 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001305618 (1) 2868bp
    Genomic GenBank:BX511227 (1) 262038bp Blast at MegaBLAST
    Polypeptide UniProtKB:Q6V9Y8 (1) 590aa
    Sequence Clusters UniGene:90210 (1)
    Sequence Information (all 15)
    OTHER gpc3 GENE PAGES
  • Gene:387365 (1)
  • VEGA:OTTDARG00000021167 (1)
  • Ensembl(GRCz10):ENSDARG00000032199 (1)
  • ORTHOLOGY for gpc3 (Chr: 14)
    CITATIONS (22)