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ZIRC
ZFIN ID: ZDB-GENE-031212-1
Gene Name: glypican 3
Gene Symbol: gpc3
Sequence Ontology ID : SO:0001217

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(Including Attributions)
Location: Chr: 14 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Involved in cell migration involved in gastrulation and negative regulation of canonical Wnt signaling pathway. Predicted to localize to the anchored component of plasma membrane; cell surface; and  ...
GENE EXPRESSION
All Expression Data: 4 figures from 2 publications
Wild-type Stages, Structures: Cleavage:8-cell (1.25h-1.5h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la018952Tg Transgenic Insertion Unknown Unknown DNA
la018953Tg Transgenic Insertion Unknown Unknown DNA
la018954Tg Transgenic Insertion Unknown Unknown DNA
la018955Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la018956Tg Transgenic Insertion Unknown Unknown DNA
    sa42411 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH gpc3 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    nephroblastoma Wilms tumor, somatic 194070
    Simpson-Golabi-Behmel syndrome type 1 Simpson-Golabi-Behmel syndrome, type 1 312870
    DISEASE ASSOCIATED WITH gpc3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process negative regulation of canonical Wnt signaling pathway (more)
    Cellular Component anchored component of membrane (more)
    GO Terms (all 19)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001863 (1)
  • InterPro:IPR015501 (1)
  • Pfam:PF01153 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA gpc3-201 (1) 2558
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM gpc3 No data available
    MARKER RELATIONSHIPS
    gpc3 Contained in: [BAC] CH211-113B2 (1) (order this), DKEY-57B1 (1) (order this), DKEY-100E19 (1) (order this), DKEY-204C2 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001305618 (1)
    Genomic GenBank:BX511227 (1) 262038 bp Blast at MegaBLAST
    Polypeptide UniProtKB:Q6V9Y8 (1) 590 aa
    Sequence Clusters UniGene:90210 (1)
    Sequence Information (all 16)
    ORTHOLOGY for gpc3 ( Chr: 14 )
    CITATIONS (27)