ZFIN ID: ZDB-GENE-031118-20
Gene Name: fucosyltransferase 8a (alpha (1,6) fucosyltransferase)
Gene Symbol: fut8a    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: fut8, wu:fd47h04

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 17 Mapping Details/Browsers
Description: Exhibits alpha-(1->6)-fucosyltransferase activity. Involved in N-glycan fucosylation. Predicted to localize to Golgi cisterna membrane and integral component of membrane. Orthologous to human FUT8 (fucosyltransferase 8).
Genome Resources: Alliance (1),  Gene:797512 (1),  Ensembl(GRCz11):ENSDARG00000015449 (2)
GENE EXPRESSION
All Expression Data: Fig. 2 from Dehnert et al., 2011
Wild-type Stages, Structures: Segmentation:10-13 somites (14.0h-16.0h) to Hatching:Long-pec (48.0h-60.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la013121Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la013122Tg Transgenic Insertion Unknown Unknown DNA
    la020101Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa14786 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa15698 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-fut8a
    3
    CRISPR2-fut8a
    3
    MO1-fut8a N/A 2
    MO2-fut8a N/A 1
    DISEASE ASSOCIATED WITH fut8a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Congenital disorder of glycosylation with defective fucosylation 1 618005
    DISEASE ASSOCIATED WITH fut8a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process N-glycan fucosylation (more)
    Cellular Component Golgi apparatus (more)
    Molecular Function alpha-(1->6)-fucosyltransferase activity (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA fut8a-201 (1)    Ensembl 3200
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM fut8a No data available
    MARKER RELATIONSHIPS
    fut8a Contained in: [BAC] CH211-237F6 (1), DKEY-25L21 (1) (order this)
    fut8a Encodes: [EST] fd47h04
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001003855 (1) 1743 nt
    Genomic GenBank:BX950853 (1) 214513 nt Blast at MegaBLAST
    Polypeptide UniProtKB:F1QW63 (1) 581 aa
    Sequence Information (all 18)
    ORTHOLOGY for fut8a ( Chr: 17 )
    CITATIONS (32)