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ZIRC
ZFIN ID: ZDB-GENE-031106-3
Gene Name: stearoyl-CoA desaturase (delta-9-desaturase)
Gene Symbol: scd    Nomenclature History

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Previous Name: SCD1 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 12 Mapping Details/Browsers
Description: Predicted to have iron ion binding activity; palmitoyl-CoA 9-desaturase activity; and stearoyl-CoA 9-desaturase activity. Predicted to be involved in monounsaturated fatty acid biosynthetic process and response to fatty acid. Predicted to localize to the integral component of endoplasmic reticulum membrane. Is expressed in brain; female organism; heart; liver; and muscle. Orthologous to several human genes including SCD5 (stearoyl-CoA desaturase 5).
Genome Resources: Alliance (1),  Gene:386661 (1),  Ensembl(GRCz11):ENSDARG00000033662 (2)
GENE EXPRESSION
All Expression Data: 12 figures from 10 publications
Wild-type Stages, Structures: Cleavage:64-cell (2.0h-2.25h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa17552 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • zf3016 Small Deletion Unknown Unknown CRISPR
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-scd 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH scd HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH scd VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process fatty acid biosynthetic process (more)
    Cellular Component integral component of membrane (more)
    Molecular Function oxidoreductase activity (more)
    GO Terms (all 15)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA scd-201 (1)    Ensembl 1537
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM scd No data available
    MARKER RELATIONSHIPS
    scd Contained in: [BAC] CH73-300E14 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_198815 (1) 1061 bp
    Genomic GenBank:FP102054 (1) 96657 bp
    Select Tool
    Polypeptide UniProtKB:F1QG70 (1) 326 aa
    Sequence Clusters UniGene:105241 (1)
    Sequence Information (all 9)
    ORTHOLOGY for scd ( Chr: 12 )
    CITATIONS (42)