Gene

pfkfb4b

ID
ZDB-GENE-031031-4
Name
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4b
Symbol
pfkfb4b Nomenclature History
Previous Names
  • pfkfb4
  • pfkfb4l
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have 6-phosphofructo-2-kinase activity and fructose-2,6-bisphosphate 2-phosphatase activity. Predicted to be involved in fructose 2,6-bisphosphate metabolic process. Predicted to localize to cytosol. Is expressed in central nervous system; forerunner cell group; intermediate cell mass of mesoderm; neural plate; and ventral mesoderm. Orthologous to human PFKFB4 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pfkfb4b Human Ortholog
No data available
Associated With pfkfb4b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site
Domain IPR013079 6-phosphofructo-2-kinase
Family IPR003094 Fructose-2,6-bisphosphatase
Family IPR013078 Histidine phosphatase superfamily, clade-1
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR029033 Histidine phosphatase superfamily
Domain Details Per Protein
Protein Length 6-phosphofructo-2-kinase Fructose-2,6-bisphosphatase Histidine phosphatase superfamily Histidine phosphatase superfamily, clade-1 Phosphoglycerate/bisphosphoglycerate mutase, active site P-loop containing nucleoside triphosphate hydrolase
UniProtKB:F6NXI0 485
UniProtKB:Q7T325 469
UniProtKB:Q6P945 453
UniProtKB:F6NIB1 504
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations