Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-031027-1
Gene Name: anaplastic lymphoma kinase (Ki-1)
Gene Symbol: alk
Previous Names: chunp9946
Nomenclature History
GENE EXPRESSION No data available
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: la020189Tg
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
{Neuroblastoma, susceptibility to, 3} 613014
GENE ONTOLOGY
Ontology GO Term
Biological Process nervous system development (more)
Cellular Component integral to membrane (more)
Molecular Function transmembrane receptor protein tyrosine kinase activity (more)
GO Terms (all 18)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000719 (1)
  • InterPro:IPR000998 (1)
  • InterPro:IPR001245 (1)
  • InterPro:IPR002011 (1)
  • InterPro:IPR008266 (1)
  • InterPro:IPR008985 (1)
  • InterPro:IPR011009 (1)
  • InterPro:IPR017441 (1)
  • InterPro:IPR020635 (1)
  • InterPro:IPR026830 (1)
  • PROSITE:PS00107 (1)
  • PROSITE:PS00109 (1)
  • PROSITE:PS00239 (1)
  • PROSITE:PS50011 (1)
  • PROSITE:PS50060 (1)
  • Pfam:PF00629 (1)
  • Pfam:PF07714 (1)
  • EC:2.7.10.1 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA alk-001 (1) 8881
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM alk No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    alk Contained in: [BAC] DKEYP-47F9
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_686872 (1) 1368 bp
    Genomic GenBank:BX663528 (1) 193986 bp
    Select Tool
    Polypeptide UniProtKB:F8W3R9 (1) 1181 aa
    Sequence Clusters UniGene:108662 (1)
    Sequence Information (all 7)
    OTHER alk GENE PAGES
  • Gene:563509 (1)
  • VEGA:OTTDARG00000033980 (1)
  • Ensembl(Zv9):ENSDARG00000095833 (1)
  • MAPPING INFORMATION
    Chr: 17 Details View Map: Merged   Individual Panels
    ORTHOLOGY
      Evidence
    Species Symbol Chromosome (Position) Accession # NT
    Zebrafish alk 17  
    Human ALK 2 (2p23)
  • OMIM:105590
  • Gene:238
  • CITATIONS (14)