Gene

tlc

ID
ZDB-GENE-031020-1
Name
secreted frizzled-related protein
Symbol
tlc Nomenclature History
Previous Names
  • sfrp
Type
protein_coding_gene
Location
Unmapped
Description
Predicted to be involved in several processes, including Wnt signaling pathway; cell differentiation; and regulation of signal transduction. Predicted to localize to extracellular region. Is expressed in forebrain neural plate; neural keel; and neural plate.
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tlc Human Ortholog
No data available
Associated With tlc Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001134 Netrin domain
Domain IPR018933 Netrin module, non-TIMP type
Domain IPR020067 Frizzled domain
Domain IPR041773 Crescent, cysteine-rich domain
Family IPR015526 Frizzled/secreted frizzled-related protein
Family IPR034860 Secreted frizzled-related protein 5
Homologous_superfamily IPR008993 Tissue inhibitor of metalloproteinases-like, OB-fold
Homologous_superfamily IPR036790 Frizzled cysteine-rich domain superfamily
Domain Details Per Protein
Protein Length Crescent, cysteine-rich domain Frizzled cysteine-rich domain superfamily Frizzled domain Frizzled/secreted frizzled-related protein Netrin domain Netrin module, non-TIMP type Secreted frizzled-related protein 5 Tissue inhibitor of metalloproteinases-like, OB-fold
UniProtKB:Q8JHC7 282
Transcripts
Genome Browsers
No data available
No data available
Interactions and Pathways
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations