Gene

satb1a

ID
ZDB-GENE-031010-36
Name
SATB homeobox 1a
Symbol
satb1a Nomenclature History
Previous Names
  • sb:cb955
  • si:ch211-195k18.2 (1)
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to have RNA polymerase II regulatory region sequence-specific DNA binding activity. Predicted to be involved in chromatin remodeling and negative regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in basal plate midbrain region and nervous system. Orthologous to human SATB1 (SATB homeobox 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Thyme et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With satb1a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
den Hoed-de Boer-Voisin syndrome 619229
Developmental delay with dysmorphic facies and dental anomalies 619228
Associated With satb1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003350 CUT domain
Domain IPR032355 SATB, CUT1-like DNA-binding domain
Domain IPR032392 SATB, ubiquitin-like oligomerisation domain
Family IPR039673 DNA-binding protein SATB1/SATB2
Homologous_superfamily IPR010982 Lambda repressor-like, DNA-binding domain superfamily
Homologous_superfamily IPR038216 SATB, CUTL domain superfamily
Homologous_superfamily IPR038224 SATB, ULD domain superfamily
Domain Details Per Protein
Protein Length CUT domain DNA-binding protein SATB1/SATB2 Lambda repressor-like, DNA-binding domain superfamily SATB, CUT1-like DNA-binding domain SATB, CUTL domain superfamily SATB, ubiquitin-like oligomerisation domain SATB, ULD domain superfamily
UniProtKB:Q1LUN2 728
UniProtKB:A0A8M2BHC4 720
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations