ZFIN ID: ZDB-GENE-031002-9
Gene Name: protein disulfide isomerase family A, member 3
Gene Symbol: pdia3    Nomenclature History

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Previous Names: erp57 (1), sb:cb825

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 25 Mapping Details/Browsers
Description: Predicted to have protein disulfide isomerase activity. Predicted to be involved in protein folding and response to endoplasmic reticulum stress. Predicted to localize to cell surface and endoplasmic reticulum. Is expressed in several structures, including axis; hatching gland; hypochord; nervous system; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in autoimmune hepatitis. Orthologous to human PDIA3 (protein disulfide isomerase family A member 3).
Genome Resources: Alliance (1),  Gene:378851 (1),  Ensembl(GRCz11):ENSDARG00000102640 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa16170 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16372 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH pdia3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH pdia3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cell redox homeostasis (more)
    Cellular Component cell surface (more)
    Molecular Function isomerase activity (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA pdia3-201 (1)    Ensembl 845
    pdia3-202 (1)    Ensembl 1753
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM pdia3 No data available
    MARKER RELATIONSHIPS
    pdia3 Contained in: [Fosmid] ZFOS-2733E12 (1)
    pdia3 Encodes: [EST] cb825 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001199737 (1) 2092 nt
    Genomic GenBank:CABZ01033639 (1) 44069 nt
    Select Tool
    Polypeptide UniProtKB:Q803D7 (1) 492 aa
    Sequence Information (all 15)
    ORTHOLOGY for pdia3 ( Chr: 25 )
    CITATIONS (27)