ZFIN ID: ZDB-GENE-031002-50
Gene Name: family with sequence similarity 49 member A
Gene Symbol: fam49a    Nomenclature History

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Previous Names: fam49ab (1), sb:cb866, si:ch211-223o11.1, si:ch211-89p3.1, zgc:55309, znf395

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 20 Mapping Details/Browsers
Description: Involved in regulation of T cell differentiation and thymus development. Is expressed in several structures, including adaxial cell; digestive system; musculature system; sensory system; and trunk. Orthologous to human CYRIA (CYFIP related Rac1 interactor A).
Genome Resources: Alliance (1),  Gene:378872 (1),  Ensembl(GRCz11):ENSDARG00000006672 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la021596Tg Transgenic Insertion Unknown Unknown DNA
sa29414 Point Mutation Unknown Premature Stop ENU
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-fam49a N/A 1
PHENOTYPE
Data: Fig. 5 from Li et al., 2016
Observed in:
DISEASE ASSOCIATED WITH fam49a HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH fam49a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process regulation of T cell differentiation (more)
Molecular Function molecular_function (more)
GO Terms (all 3)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA fam49a-201 (1)    Ensembl 1851
fam49a-203 (1)    Ensembl 1850
fam49a-206 (1)    Ensembl 889
ncRNA znf395-003 (1)    Ensembl 302
znf395-004 (1)    Ensembl 892
znf395-006 (1)    Ensembl 738
znf395-007 (1)    Ensembl 729
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM fam49a No data available
MARKER RELATIONSHIPS
fam49a Contained in: [BAC] CH211-89P3 (1), CH211-223O11 (1)
fam49a Encodes: [EST] cb866 (1) (order this)
[cDNA] MGC:55309 (1), MGC:77190 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_200108 (1) 1859 nt
Genomic GenBank:BX511007 (1) 174463 nt
Select Tool
Polypeptide UniProtKB:A0A0R4IMR9 (1) 381 aa
Sequence Information (all 53)
ORTHOLOGY for fam49a ( Chr: 20 )
CITATIONS (28)