Gene
atp2b1a
- ID
- ZDB-GENE-030925-29
- Name
- ATPase plasma membrane Ca2+ transporting 1a
- Symbol
- atp2b1a Nomenclature History
- Previous Names
-
- pmca1a (1)
- sb:cb801
- si:dkey-18o7.1
- wu:fe47b06
- wu:fi41d01
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to have PDZ domain binding activity and calcium transmembrane transporter activity, phosphorylative mechanism. Involved in animal organ development and sensory perception of sound. Predicted to localize to intracellular membrane-bounded organelle. Is expressed in several structures, including digestive system; hematopoietic system; midbrain neural tube; nervous system; and pleuroperitoneal region. Orthologous to human ATP2B1 (ATPase plasma membrane Ca2+ transporting 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 24 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb801 (12 images)
- IMAGE:7139107 (10 images)
- IMAGE:7165930 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Intellectual developmental disorder, autosomal dominant 66 | 619910 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR004014 | Cation-transporting P-type ATPase, N-terminal |
| Domain | IPR006068 | Cation-transporting P-type ATPase, C-terminal |
| Domain | IPR022141 | Plasma membrane calcium transporting P-type ATPase, C-terminal |
| Domain | IPR044492 | P-type ATPase, haloacid dehalogenase domain |
| Family | IPR001757 | P-type ATPase |
| Family | IPR006408 | P-type ATPase, subfamily IIB |
| Homologous_superfamily | IPR008250 | P-type ATPase, A domain superfamily |
| Homologous_superfamily | IPR023214 | HAD superfamily |
| Homologous_superfamily | IPR023298 | P-type ATPase, transmembrane domain superfamily |
| Homologous_superfamily | IPR023299 | P-type ATPase, cytoplasmic domain N |
| Homologous_superfamily | IPR036412 | HAD-like superfamily |
| PTM | IPR018303 | P-type ATPase, phosphorylation site |
Domain Details Per Protein
| Protein | Length | Cation-transporting P-type ATPase, C-terminal | Cation-transporting P-type ATPase, N-terminal | HAD-like superfamily | HAD superfamily | Plasma membrane calcium transporting P-type ATPase, C-terminal | P-type ATPase | P-type ATPase, A domain superfamily | P-type ATPase, cytoplasmic domain N | P-type ATPase, haloacid dehalogenase domain | P-type ATPase, phosphorylation site | P-type ATPase, subfamily IIB | P-type ATPase, transmembrane domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q1RM46
|
304 | ||||||||||||
|
UniProtKB:Q6DGN2
|
304 | ||||||||||||
|
UniProtKB:A1L214
|
315 | ||||||||||||
|
UniProtKB:Q569P8
|
334 | ||||||||||||
|
UniProtKB:F6PDY7
|
1228 | ||||||||||||
|
UniProtKB:Q5RGZ4
|
1215 | ||||||||||||
|
UniProtKB:Q0V934
|
311 |
| Type | Name | Length (nt) | Analysis |
|---|---|---|---|
| mRNA |
atp2b1a-201
(1)
|
5951 nt |
Interactions and Pathways
No data available
Plasmids
No data available