ZFIN Gene: atp2b1a

ZFIN ID: ZDB-GENE-030925-29

ZFIN ID: ZDB-GENE-030925-29

Gene Name:

ATPase plasma membrane Ca2+ transporting 1a

Gene Symbol:

atp2b1a

Sequence Ontology ID :

SO:0000704

Previous Names:

pmca1a (1), sb:cb801, si:dkey-18o7.1, wu:fe47b06, wu:fi41d01

Location:

Chr: 4 Mapping Details/Browsers

Nomenclature History

AUTOMATED DESCRIPTION

Predicted to have PDZ domain binding activity and calcium-transporting ATPase activity; involved in several processes, including animal organ development, animal organ development, and sensory ...

GENE EXPRESSION
All Expression Data:	24 figures from 7 publications
Directly Submitted Expression Data:	6 figures (12 images) from Thisse et al., 2001 [cb801]
	6 figures (10 images) from Thisse et al., 2004 [IMAGE:7139107]
	4 figures (16 images) from Rauch et al., 2003 [fq35e10]
	1 figure (1 image) from Thisse et al., 2004 [IMAGE:7165930]
Wild-type Stages, Structures:	Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
	alar plate midbrain region basal plate midbrain region blood brain central nervous system cranial ganglion diencephalon eye gill hair cell anterior macula hair cell posterior macula hindbrain infraorbital lateral line neuromast inner ear integument intermediate cell mass of mesoderm intestine kidney lagena lateral line system lens liver macula macula lagena hair cell macula lagena mandibular lateral line neuromast midbrain middle lateral line neuromast muscle pioneer neuromast neuron occipital lateral line neuromast olfactory placode opercular lateral line neuromast optic stalk optic tectum otic lateral line neuromast otic placode otic vesicle ovary peripheral olfactory organ pharyngeal epithelium posterior lateral line neuromast posterior lateral line primordium protoneuromast primary neuron retina saccule solid lens vesicle somite spinal cord spleen tegmentum telencephalon tooth 4V tooth placode trigeminal placode ventral mesoderm whole organism yolk syncytial layer
Curated Microarray Expression:	GEO (1)

MUTATIONS AND SEQUENCE TARGETING REAGENTS

Allele	Type	Localization	Consequence	Mutagen	Suppliers
sa33434	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa40264	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)

Targeting reagents:

MO1-atp2b1a (1)
MO2-atp2b1a (1)

PHENOTYPE

Data:

9 figures from 3 publications

Observed in:

DISEASE ASSOCIATED WITH atp2b1a HUMAN ORTHOLOG No data available

DISEASE ASSOCIATED WITH atp2b1a VIA EXPERIMENTAL MODELS No data available

GENE ONTOLOGY

Ontology	GO Term
Biological Process	bone mineralization (more)
Cellular Component	integral component of membrane (more)
Molecular Function	ATP binding (more)

GO Terms (all 20)

PROTEIN FAMILIES, DOMAINS AND SITES
InterPro:IPR001757 (1) InterPro:IPR004014 (1) InterPro:IPR006068 (1) InterPro:IPR006408 (1) InterPro:IPR008250 (1) InterPro:IPR018303 (1) InterPro:IPR022141 (1) InterPro:IPR023214 (1) InterPro:IPR023298 (1) InterPro:IPR023299 (1) InterPro:IPR030320 (1) InterPro:IPR030322 (1) InterPro:IPR036412 (1)	PROSITE:PS00154 (1)	Pfam:PF00689 (1) Pfam:PF00690 (1) Pfam:PF12424 (1)	EC:7.2.2.10 (1)

TRANSCRIPTS
Type	Name	Length (bp)	Analysis
mRNA	atp2b1a-201 (1)	5951	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

GENE PRODUCT DESCRIPTION

INTERACTIONS AND PATHWAYS

ANTIBODIESNo data available

PLASMIDSNo data available

CONSTRUCTS WITH SEQUENCES FROM atp2b1a No data available

MARKER RELATIONSHIPS

atp2b1aContained in:	[BAC] DKEY-18O7 (1) (order this)
atp2b1aEncodes:	[EST] cb801 (1) (order this), fe47b06 (1), fi41d01 (1), fq35e10 (1) (order this), IMAGE:7139107 (1) (order this), IMAGE:7165930 (1) (order this) [cDNA] MGC:198349 (1) (order this)

SEQUENCE INFORMATION

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_001044757 (1)	5951bp	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:BX649423 (1)	182374bp	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:F6PDY7 (1)	1228aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast
Sequence Clusters	UniGene:76148 (1)

Sequence Information (all 47)

OTHER atp2b1a GENE PAGES

Alliance (1)

Gene:378746 (1)

VEGA:OTTDARG00000011295 (1)

Ensembl(GRCz11):ENSDARG00000012684 (2)

ORTHOLOGY for atp2b1a (Chr: 4)

CITATIONS (33)

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