Gene

siah2l

ID
ZDB-GENE-030922-1
Name
seven in absentia homolog 2 (Drosophila)-like
Symbol
siah2l Nomenclature History
Previous Names
  • siaz (1)
  • zgc:66284
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to have ubiquitin conjugating enzyme binding activity and ubiquitin protein ligase activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process and regulation of circadian rhythm. Predicted to localize to cytoplasm. Is expressed in dorsal aorta; gut; male organism; nervous system; and otic vesicle. Orthologous to human SIAH2 (siah E3 ubiquitin protein ligase 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
9 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With siah2l Human Ortholog
No data available
Associated With siah2l Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001841 Zinc finger, RING-type
Domain IPR013010 Zinc finger, SIAH-type
Domain IPR018121 Seven-in-absentia protein, TRAF-like domain
Family IPR004162 E3 ubiquitin-protein ligase SINA-like, animal
Homologous_superfamily IPR008974 TRAF-like
Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
Domain Details Per Protein
Protein Length E3 ubiquitin-protein ligase SINA-like, animal Seven-in-absentia protein, TRAF-like domain TRAF-like Zinc finger, RING/FYVE/PHD-type Zinc finger, RING-type Zinc finger, SIAH-type
UniProtKB:B5DDM1 207
UniProtKB:Q7SYL3 331
UniProtKB:G8JL17 330
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations