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ZIRC
ZFIN ID: ZDB-GENE-030918-5
Gene Name: erb-b2 receptor tyrosine kinase 4b
Gene Symbol: erbb4b    Nomenclature History

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Previous Names: erbb4l, si:dkeyp-52f4.1, zmp:0000000963

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Predicted to have transmembrane receptor protein tyrosine kinase activity. Predicted to be involved in positive regulation of cell population proliferation and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to localize to the basal plasma membrane; integral component of plasma membrane; and receptor complex. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 19 and colorectal cancer. Is expressed in heart. Orthologous to human ERBB4 (erb-b2 receptor tyrosine kinase 4).
Genome Resources: Alliance (1),  Ensembl(GRCz11):ENSDARG00000089536 (2)
GENE EXPRESSION
All Expression Data: Fig. 3 from Samsa et al., 2016
Wild-type Stages, Structures: Larval:Protruding-mouth (72.0h-96.0h, 3.5mm) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
PHENOTYPE No data available
DISEASE ASSOCIATED WITH erbb4b HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
amyotrophic lateral sclerosis type 19 Alliance Amyotrophic lateral sclerosis 19 615515
DISEASE ASSOCIATED WITH erbb4b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process phosphorylation (more)
Cellular Component integral component of membrane (more)
Molecular Function ATP binding (more)
GO Terms (all 18)
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA erbb4b-202 (1)    Ensembl 2220
Browsers: EnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM erbb4b No data available
MARKER RELATIONSHIPS
erbb4b Contained in: [BAC] DKEYP-52F4
[Fosmid] CH1073-160H5 (1) (order this)
erbb4b Contains: [STS] zfish35937-102f03.p1c (1)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
Genomic GenBank:CR762391 177067 bp
Select Tool
Polypeptide UniProtKB:A0A2R8QJK4 (1) 857 aa
Sequence Information (all 6)
ORTHOLOGY for erbb4b ( Chr: 9 )
CITATIONS (21)