ZFIN ID: ZDB-GENE-030912-15
Gene Name: retinol dehydrogenase 1
Gene Symbol: rdh1    Nomenclature History

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Previous Name: RDHB (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Exhibits retinol dehydrogenase activity. Involved in several processes, including embryonic pectoral fin morphogenesis; pancreas development; and retinoid metabolic process. Predicted to localize to the integral component of membrane. Is expressed in intestinal bulb and liver.
Genome Resources: Alliance (1),  Gene:378440 (1),  Ensembl(GRCz11):ENSDARG00000017882 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 3 figures (4 images) from Thisse et al., 2004 [MGC:56342]
Wild-type Stages, Structures: Pharyngula:High-pec (42.0h-48.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la016625Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la027054Tg Transgenic Insertion Unknown Unknown DNA
    sa7214 Point Mutation Unknown Splice Site ENU
    sa34767 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-rdh1 N/A 2
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH rdh1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH rdh1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process embryonic heart tube development (more)
    Cellular Component integral component of membrane (more)
    Molecular Function retinol dehydrogenase activity (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Family IPR002347 Short-chain dehydrogenase/reductase SDR
    Homologous_superfamily IPR036291 NAD(P)-binding domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA rdh1-201 (1)    Ensembl 1816
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM rdh1 No data available
    MARKER RELATIONSHIPS
    rdh1 Contained in: [BAC] CH211-121K8 (1)
    rdh1 Encodes: [cDNA] MGC:56342 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_198069 (1) 1170 bp
    Genomic GenBank:BX927361 (1) 177986 bp
    Select Tool
    Polypeptide UniProtKB:A0A286Y8B5 (1) 327 aa
    Sequence Information (all 13)
    ORTHOLOGY for rdh1 ( Chr: 9 )
    CITATIONS (28)