ZFIN ID: ZDB-GENE-030912-13
Gene Name: bone morphogenetic protein 8a
Gene Symbol: bmp8a    Nomenclature History

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Previous Name: bmp8 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 19 Mapping Details/Browsers
Description: Predicted to have BMP receptor binding activity and cytokine activity. Predicted to be involved in BMP signaling pathway; SMAD protein signal transduction; and positive regulation of pathway-restricted SMAD protein phosphorylation. Predicted to localize to extracellular space. Is expressed in caudal fin. Orthologous to several human genes including BMP8A (bone morphogenetic protein 8a).
Genome Resources: Alliance (1),  Gene:561963 (1),  Ensembl(GRCz11):ENSDARG00000035677 (1)
GENE EXPRESSION
All Expression Data: Fig. 3 from Schebesta et al., 2006
Wild-type Stages, Structures: Adult (90d-730d, breeding adult) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la020791Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa10778 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH bmp8a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH bmp8a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process BMP signaling pathway (more)
    Cellular Component extracellular region (more)
    Molecular Function growth factor activity (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA bmp8a-201 (1)    Ensembl 1553
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM bmp8a No data available
    MARKER RELATIONSHIPS
    bmp8a Contained in: [BAC] RP71-45K5 (1)
    bmp8a Encodes: [EST] faa70e02
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001044971 (1) 1553 nt
    Genomic GenBank:BX511004 (1) 168626 nt
    Select Tool
    Polypeptide UniProtKB:Q1LWW7 (1) 433 aa
    Sequence Information (all 8)
    ORTHOLOGY for bmp8a ( Chr: 19 )
    CITATIONS (28)