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Gene

bmp8a

ID
ZDB-GENE-030912-13
Name
bone morphogenetic protein 8a
Symbol
bmp8a Nomenclature History
Previous Names
  • bmp8 (1)
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to enable BMP receptor binding activity and cytokine activity. Predicted to be involved in BMP signaling pathway; SMAD protein signal transduction; and positive regulation of pathway-restricted SMAD protein phosphorylation. Predicted to be located in extracellular region and membrane. Predicted to be integral component of membrane. Predicted to be active in extracellular space. Is expressed in caudal fin. Orthologous to several human genes including BMP8A (bone morphogenetic protein 8a).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Schebesta et al., 2006
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With bmp8a Human Ortholog
No data available
Associated With bmp8a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017948 Transforming growth factor beta, conserved site
Domain IPR001111 TGF-beta, propeptide
Domain IPR001839 Transforming growth factor-beta, C-terminal
Family IPR015615 Transforming growth factor-beta-related
Homologous_superfamily IPR029034 Cystine-knot cytokine
Domain Details Per Protein
Protein Length Cystine-knot cytokine TGF-beta, propeptide Transforming growth factor beta, conserved site Transforming growth factor-beta, C-terminal Transforming growth factor-beta-related
UniProtKB:Q1LWW7 433
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations