ZFIN ID: ZDB-GENE-030912-11
Gene Name: alpha thalassemia/mental retardation syndrome X-linked homolog (human)
Gene Symbol: atrx
Previous Names: wu:fb26e12, wu:fb52h08, wu:fb72g09
Location: Chr: 14 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:66223]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
  unspecified
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Allele Type Mutagen Suppliers
la027489Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa10556 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa13757 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa15167 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa17647 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents: MO1-atrx (1)
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH atrx HUMAN ORTHOLOG 
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    alpha thalassemia Alpha-thalassemia/mental retardation syndrome 301040
    Mental retardation-hypotonic facies syndrome, X-linked 309580
    Mental retardation, X-linked 52
    Alpha-thalassemia myelodysplasia syndrome, somatic 300448
    GENE ONTOLOGY 
    Ontology GO Term
    Molecular Function ATP binding (more)
    GO Terms (all 2)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000330 (1)
  • InterPro:IPR001650 (1)
  • InterPro:IPR001841 (1)
  • InterPro:IPR011011 (1)
  • InterPro:IPR013083 (1)
  • InterPro:IPR014001 (1)
  • InterPro:IPR025766 (1)
  • InterPro:IPR027417 (1)
  • PROSITE:PS51192 (1)
  • PROSITE:PS51194 (1)
  • PROSITE:PS51533 (1)
  • Pfam:PF00176 (1)
  • Pfam:PF00271 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA atrx-001 (1) 8416
    ncRNA atrx-002 (1) 581
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM atrx No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    atrxContained in: [BAC] DKEY-65A17 (1) (order this), DKEY-92I17 (1) (order this)
    atrxEncodes: [EST] faa09a05, fb26e12, fb52h08, fb72g09, fb94e07
    [cDNA] MGC:66223 (1) (order this)
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_200653 (1) 7483bp
    Genomic GenBank:CR931764 (1) 180522bp
    Select Tool
    Polypeptide UniProtKB:E7F4M2 (1) 2013aa
    Sequence Clusters UniGene:5568 (1)
    Sequence Information (all 29)
    OTHER atrx GENE PAGES 
  • Gene:323299 (1)
  • VEGA:OTTDARG00000032075 (1)
  • Ensembl(GRCz10):ENSDARG00000042236 (1)
  • ORTHOLOGY for atrx (Chr: 14) 
    Species Symbol Chromosome Accession # Evidence
    Human ATRX X
  • Gene:546
  • OMIM:300032
  • HGNC:886
  • Amino acid sequence comparison (1)
    Mouse Atrx X
  • MGI:103067
  • Gene:22589
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (20)