ZFIN ID: ZDB-GENE-030912-11
Gene Name: alpha thalassemia/mental retardation syndrome X-linked homolog (human)
Gene Symbol: atrx
Previous Names: wu:fb26e12, wu:fb52h08, wu:fb72g09
Location: Chr: 14 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:66223]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
  unspecified
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la027489Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa10556 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa13757 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa15167 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa17647 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa35643 Point Mutation Unknown Unknown ENU
    sa35644 Point Mutation Unknown Unknown ENU
    sa35645 Point Mutation Unknown Unknown ENU
    sa42354 Point Mutation Unknown Unknown ENU
    Targeting reagents: MO1-atrx (1)
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH atrx HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    alpha thalassemia-X-linked intellectual disability syndrome Alpha-thalassemia/mental retardation syndrome 301040
    Mental retardation-hypotonic facies syndrome, X-linked 309580
    Mental retardation, X-linked 52
    Alpha-thalassemia myelodysplasia syndrome, somatic 300448
    GENE ONTOLOGY
    Ontology GO Term
    Molecular Function ATP binding (more)
    GO Terms (all 1)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000330 (1)
  • InterPro:IPR001650 (1)
  • InterPro:IPR011011 (1)
  • InterPro:IPR013083 (1)
  • InterPro:IPR014001 (1)
  • InterPro:IPR025766 (1)
  • InterPro:IPR027417 (1)
  • PROSITE:PS51192 (1)
  • PROSITE:PS51194 (1)
  • PROSITE:PS51533 (1)
  • Pfam:PF00176 (1)
  • Pfam:PF00271 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA atrx-001 (1) 8416
    ncRNA atrx-002 (1) 581
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM atrx No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    atrxContained in: [BAC] DKEY-65A17 (1) (order this), DKEY-92I17 (1) (order this)
    atrxEncodes: [EST] faa09a05, fb26e12, fb52h08, fb72g09, fb94e07
    [cDNA] MGC:66223 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_200653 (1) 7483bp
    Genomic GenBank:CR931764 (1) 180522bp
    Select Tool
    Polypeptide UniProtKB:E7F4M2 (1) 2013aa
    Sequence Clusters UniGene:5568 (1)
    Sequence Information (all 29)
    OTHER atrx GENE PAGES
  • Gene:323299 (1)
  • VEGA:OTTDARG00000032075 (1)
  • Ensembl(GRCz10):ENSDARG00000042236 (1)
  • ORTHOLOGY for atrx (Chr: 14)
    Species Symbol Chromosome Accession # Evidence
    Human ATRX X
  • Gene:546
  • OMIM:300032
  • OMIM:300504
  • HGNC:886
  • Amino acid sequence comparison (1)
    Mouse Atrx X
  • MGI:103067
  • Gene:22589
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (20)