ZFIN ID: ZDB-GENE-030912-11
Gene Name: alpha thalassemia/mental retardation syndrome X-linked homolog (human)
Gene Symbol: atrx
Previous Names: wu:fb26e12, wu:fb52h08, wu:fb72g09
Location: Chr: 14   Details
Nomenclature History
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:66223]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
  unspecified
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: la027489Tg, sa10556, sa13757, sa15167, sa17647
Knockdown reagents: MO1-atrx (1)
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Alpha-thalassemia myelodysplasia syndrome, somatic 300448
Alpha-thalassemia/mental retardation syndrome 301040
Mental retardation-hypotonic facies syndrome, X-linked 309580
GENE ONTOLOGY
Ontology GO Term
Molecular Function ATP binding (more)
GO Terms (all 3)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000330 (1)
  • InterPro:IPR001650 (1)
  • InterPro:IPR001841 (1)
  • InterPro:IPR011011 (1)
  • InterPro:IPR013083 (1)
  • InterPro:IPR014001 (1)
  • InterPro:IPR025766 (1)
  • InterPro:IPR027417 (1)
  • PROSITE:PS51192 (1)
  • PROSITE:PS51194 (1)
  • PROSITE:PS51533 (1)
  • Pfam:PF00176 (1)
  • Pfam:PF00271 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA atrx-001 (1) 8416
    ncRNA atrx-002 (1) 581
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM atrx No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    atrx Contained in: [BAC] DKEY-65A17 (1), DKEY-92I17 (1)
    atrx Encodes: [EST] faa09a05, fb26e12, fb52h08, fb72g09, fb94e07
    [cDNA] MGC:66223 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA GenBank:BC047849 3187 bp
    Genomic GenBank:CR931764 (1) 180522 bp
    Select Tool
    Polypeptide UniProtKB:E7F4M2 (1) 2011 aa
    Sequence Information (all 18)
    OTHER atrx GENE PAGES
  • VEGA:OTTDARG00000032075 (1)
  • Ensembl(Zv9):ENSDARG00000042236 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish atrx 14  
    Human ATRX X (Xq21.1)
  • OMIM:300032
  • Gene:546
  • Mouse Atrx X ( 47.26 cM)
  • MGI:103067
  • Gene:22589
  • Orthology Details
    CITATIONS (19)