ZFIN ID: ZDB-GENE-030912-10
Gene Name: host cell factor C1a
Gene Symbol: hcfc1a    Nomenclature History

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Previous Names: hcfc1, etID52682.11 (1), fc61g09, im:7159458, wu:fc61g09 (1), wu:fj40c12

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 11 Mapping Details/Browsers
Description: Predicted to have chromatin binding activity and transcription factor binding activity. Predicted to be involved in chromatin remodeling and regulation of transcription, DNA-templated. Predicted to localize to Ada2/Gcn5/Ada3 transcription activator complex. Human ortholog(s) of this gene implicated in methylmalonic acidemia and homocysteinemia cblX type. Orthologous to human HCFC1 (host cell factor C1).
Genome Resources: Alliance (1),  Gene:564853 (1),  Ensembl(GRCz11):ENSDARG00000015990 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7159458]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la017800Tg Transgenic Insertion Unknown Unknown DNA
la027259Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21913 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-hcfc1a N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH hcfc1a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    methylmalonic acidemia and homocysteinemia cblX type Alliance Mental retardation, X-linked 3 (methylmalonic acidemia and homocysteinemia, cblX type ) 309541
    DISEASE ASSOCIATED WITH hcfc1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process chromatin remodeling (more)
    Cellular Component MLL1 complex (more)
    Molecular Function chromatin binding (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA hcfc1a-201 (1)    Ensembl 6964
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM hcfc1a No data available
    MARKER RELATIONSHIPS
    hcfc1a Contained in: [BAC] DKEY-13A21 (order this), DKEY-245F22 (1) (order this), DKEYP-97E7 (1)
    hcfc1a Encodes: [EST] fc61g09, fj40c12, IMAGE:7159458 (1)
    [cDNA] MGC:158156 (1), MGC:158300 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001045064 (1) 6952 nt
    Genomic GenBank:AL844847 235174 nt Blast at MegaBLAST
    Polypeptide UniProtKB:F1Q750 (1) 1802 aa
    Sequence Information (all 31)
    ORTHOLOGY for hcfc1a ( Chr: 11 )
    CITATIONS (30)