ZFIN ID: ZDB-GENE-030903-3
Gene Name: nuclear receptor subfamily 1, group I, member 2
Gene Symbol: nr1i2    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name: PXR (1)

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Exhibits nuclear receptor activity and steroid hormone receptor activity. Involved in regulation of transcription, DNA-templated; response to toxic substance; and transcription by RNA polymerase II. Predicted to localize to the RNA polymerase II transcription factor complex. Is expressed in several structures, including adenohypophyseal placode; brain; heart; liver; and pleuroperitoneal region. Orthologous to human NR1I2 (nuclear receptor subfamily 1 group I member 2).
Genome Resources: Alliance (1),  Gene:565875 (1),  Ensembl(GRCz11):ENSDARG00000029766 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la027133Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa1903 Point Mutation Unknown Splice Site ENU
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-nr1i2 N/A 1
    MO2-nr1i2 N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH nr1i2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH nr1i2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of transcription, DNA-templated (more)
    Cellular Component nucleus (more)
    Molecular Function DNA-binding transcription factor activity, RNA polymerase II-specific (more)
    GO Terms (all 28)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR000536 Nuclear hormone receptor, ligand-binding domain
    Domain IPR001628 Zinc finger, nuclear hormone receptor-type
    Family IPR001723 Nuclear hormone receptor
    Homologous_superfamily IPR013088 Zinc finger, NHR/GATA-type
    Homologous_superfamily IPR035500 Nuclear hormone receptor-like domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA nr1i2-202 (1)    Ensembl 2502
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM nr1i2 No data available
    MARKER RELATIONSHIPS
    nr1i2 Contained in: [BAC] DKEY-265I7 (1) (order this)
    nr1i2 Encodes: [EST] af502918 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001098617 (1) 2467 bp
    Genomic GenBank:CR848676 (1) 96536 bp
    Select Tool
    Polypeptide UniProtKB:A0A3G3LJZ1 (1) 431 aa
    Sequence Information (all 34)
    ORTHOLOGY for nr1i2 ( Chr: 9 )
    CITATIONS (66)