ZFIN Gene: cyp1b1

ZFIN ID: ZDB-GENE-030902-1

ZFIN ID: ZDB-GENE-030902-1

Gene Name:	cytochrome P450, family 1, subfamily B, polypeptide 1
Gene Symbol:	cyp1b1
Previous Name:	zgc:136223
Location:	Chr: 13 Details
Nomenclature History

GENE EXPRESSION
All Expression Data:	14 figures from 6 publications
Wild-type Stages, Structures:	Gastrula:75%-epiboly (8.0h-9.0h) to Adult (90d-730d, breeding adult)
	brain , diencephalon , eye , gill (all 13)
Curated Microarray Expression:	GEO (1)

MUTANTS AND TARGETED KNOCKDOWNS

Knockdown reagents:

MO1-cyp1b1 (1), MO2-cyp1b1 (1)

PHENOTYPE

Phenotype of Human Orthologue	OMIM Phenotype ID
Glaucoma 3A, primary open angle, congenital, juvenile, or adult onset	231300
Peters anomaly	604229

GENE ONTOLOGY

Ontology	GO Term
Biological Process	oxidation-reduction process (more)
Cellular Component	endoplasmic reticulum (more)
Molecular Function	aromatase activity (more)

GO Terms (all 12)

PROTEIN FAMILIES, DOMAINS AND SITES
InterPro:IPR001128 (1) InterPro:IPR002401 (1) InterPro:IPR008066 (1) InterPro:IPR017972 (1)	PROSITE:PS00086 (1)	Pfam:PF00067 (1)	EC:1.14.14.1 (1)

TRANSCRIPTS
Type	Name	Length (bp)	Analysis
mRNA	cyp1b1-001 (1)	2422	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT Vega
aberrant processed transcript	cyp1b1-002 (1)	3257	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT Vega

GENE PRODUCT DESCRIPTION

ANTIBODIES No data available

PLASMIDS No data available

CONSTRUCTS WITH SEQUENCES FROM cyp1b1 No data available

SEGMENT (CLONE AND PROBE) RELATIONSHIPS

cyp1b1 Contained in:	[BAC] DKEY-18N13 (1) (order this)
cyp1b1 Encodes:	[cDNA] MGC:136223 (1) (order this), MGC:194048 (1) (order this)

SEQUENCE INFORMATION

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_001145708 (1)	3257 bp	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT Vega
Genomic	GenBank:CT583720 (1)	215665 bp	Blast at MegaBLAST
Polypeptide	UniProtKB:B8JKD5 (1)	526 aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast Vega Protein Blast
Sequence Clusters	UniGene:151870 (1)

OTHER cyp1b1 GENE PAGES

Gene:100150054 (1)

VEGA:OTTDARG00000027793 (1)

Ensembl(Zv9):ENSDARG00000068934 (1)

ORTHOLOGY

CITATIONS (48)