ZFIN ID: ZDB-GENE-030902-1
Gene Name: cytochrome P450, family 1, subfamily B, polypeptide 1
Gene Symbol: cyp1b1
Previous Name: zgc:136223
Location: Chr: 13 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 14 figures from 6 publications
Wild-type Stages, Structures: Gastrula:75%-epiboly (8.0h-9.0h) to Adult (90d-730d, breeding adult)
  brain, diencephalon, epithelial cell, eye (all 17) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Targeting reagents: MO1-cyp1b1 (1), MO2-cyp1b1 (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH cyp1b1 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
buphthalmos Glaucoma 3A, primary open angle, congenital, juvenile, or adult onset 231300
Peters anomaly 604229
GENE ONTOLOGY
Ontology GO Term
Biological Process oxidation-reduction process (more)
Cellular Component endoplasmic reticulum (more)
Molecular Function aromatase activity (more)
GO Terms (all 15)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001128 (1)
  • InterPro:IPR002401 (1)
  • InterPro:IPR008066 (1)
  • InterPro:IPR017972 (1)
  • InterPro:IPR032971 (1)
  • PROSITE:PS00086 (1)
  • Pfam:PF00067 (1)
  • EC:1.14.14.1 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA cyp1b1-001 (1) 2422
    aberrant processed transcript cyp1b1-002 (1) 3257
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM cyp1b1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    cyp1b1Contained in: [BAC] DKEY-18N13 (1) (order this)
    cyp1b1Encodes: [cDNA] MGC:136223 (1) (order this), MGC:194048 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001145708 (1) 3257bp
    Genomic GenBank:CT583720 (1) 215665bp Blast at MegaBLAST
    Polypeptide UniProtKB:B8JKD5 (1) 526aa
    Sequence Clusters UniGene:151870 (1)
    Sequence Information (all 25)
    OTHER cyp1b1 GENE PAGES
  • Gene:100150054 (1)
  • VEGA:OTTDARG00000027793 (1)
  • Ensembl(GRCz10):ENSDARG00000068934 (1)
  • ORTHOLOGY for cyp1b1 (Chr: 13)
    Species Symbol Chromosome Accession # Evidence
    Human CYP1B1 2
  • Gene:1545
  • OMIM:601771
  • HGNC:2597
  • Amino acid sequence comparison (5)
    Conserved genome location (synteny) (2)
    Mouse Cyp1b1 17
  • MGI:88590
  • Gene:13078
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (68)