Community Action Needed: Please respond to the NIH RFI
Gene

ppp3cca

ID
ZDB-GENE-030829-36
Name
protein phosphatase 3, catalytic subunit, gamma isozyme, a
Symbol
ppp3cca Nomenclature History
Previous Names
  • ppp3cc
  • PPP3CCa (1)
  • sb:cb767
  • si:dkey-21k4.5 (1)
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to enable calmodulin binding activity and calmodulin-dependent protein phosphatase activity. Predicted to be involved in calcineurin-mediated signaling. Predicted to be part of calcineurin complex. Predicted to be active in cytoplasm. Is expressed in several structures, including hatching gland; musculature system; nervous system; polster; and trigeminal placode. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human PPP3CC (protein phosphatase 3 catalytic subunit gamma).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from Thisse et al., 2001
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ppp3cca Human Ortholog
No data available
Associated With ppp3cca Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR004843 Calcineurin-like phosphoesterase domain, ApaH type
Domain IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase
Domain IPR041751 PP2B, metallophosphatase domain
Family IPR043360 PP2B
Homologous_superfamily IPR029052 Metallo-dependent phosphatase-like
Domain Details Per Protein
Protein Length Calcineurin-like phosphoesterase domain, ApaH type Metallo-dependent phosphatase-like PP2B PP2B, metallophosphatase domain Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase
UniProtKB:A3KGZ6 499
UniProtKB:A0A286YA34 508
UniProtKB:A0A0R4ICR2 503
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations