ZFIN ID: ZDB-GENE-030826-6
Gene Name: eph receptor A4b
Gene Symbol: epha4b    Nomenclature History

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Previous Names: EphA3 (4), epha4, id:ibd2782, rtk2 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Predicted to have transmembrane-ephrin receptor activity. Involved in negative regulation of axon extension; negative regulation of collateral sprouting of intact axon in response to injury; and regulation of myelination. Predicted to localize to integral component of plasma membrane; neuron projection; and receptor complex. Is expressed in several structures, including axis; immature eye; intestinal bulb primordium; nervous system; and pharyngeal arch.
Genome Resources: Alliance (1),  Gene:64270 (1),  Ensembl(GRCz11):ENSDARG00000011600 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la023685Tg Transgenic Insertion Unknown Unknown DNA
mn0046Gt Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa13595 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39899 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-epha4b N/A 2
    MO2-epha4b N/A 2
    DISEASE ASSOCIATED WITH epha4b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH epha4b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process negative regulation of axon extension (more)
    Cellular Component integral component of membrane (more)
    Molecular Function ATP binding (more)
    GO Terms (all 23)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA epha4b-002 (1) 132
    Browsers: NCBI
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM epha4b No data available
    MARKER RELATIONSHIPS
    epha4b Contained in: [BAC] CH211-122L24 (1), CH211-188I21 (1), DKEY-69P21 (1) (order this)
    epha4b Encodes: [EST] ibd2782
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_153658 (1) 3319 nt
    Genomic GenBank:CR931819 (1) 197810 nt
    Select Tool
    Polypeptide UniProtKB:F1RCL1 (1) 976 aa
    Sequence Information (all 17)
    ORTHOLOGY for epha4b ( Chr: 2 )
    CITATIONS (63)