Gene
casp6a
- ID
- ZDB-GENE-030825-4
- Name
- caspase 6, apoptosis-related cysteine peptidase a
- Symbol
- casp6a Nomenclature History
- Previous Names
-
- casp6
- caspase-6a (1)
- zgc:112960
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have cysteine-type endopeptidase activity involved in execution phase of apoptosis. Predicted to be involved in apoptotic process. Predicted to localize to cytoplasm. Is expressed in several structures, including gut; integument; liver; muscle cell; and solid lens vesicle. Human ortholog(s) of this gene implicated in ovarian carcinoma. Orthologous to human CASP6 (caspase 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR016129 | Peptidase family C14A, His active site |
| Domain | IPR001309 | Peptidase C14, p20 domain |
| Domain | IPR002138 | Peptidase C14, caspase non-catalytic subunit p10 |
| Domain | IPR011600 | Peptidase C14, caspase domain |
| Domain | IPR015917 | Peptidase C14A, caspase catalytic domain |
| Homologous_superfamily | IPR029030 | Caspase-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Caspase-like domain superfamily | Peptidase C14A, caspase catalytic domain | Peptidase C14, caspase domain | Peptidase C14, caspase non-catalytic subunit p10 | Peptidase C14, p20 domain | Peptidase family C14A, His active site |
|---|---|---|---|---|---|---|---|
|
UniProtKB:F1R2P5
|
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|
UniProtKB:Q52KK6
|
298 |
Interactions and Pathways
No data available
Plasmids
No data available