Gene

casp6a

ID
ZDB-GENE-030825-4
Name
caspase 6, apoptosis-related cysteine peptidase a
Symbol
casp6a Nomenclature History
Previous Names
  • casp6
  • caspase-6a (1)
  • zgc:112960
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have cysteine-type endopeptidase activity involved in execution phase of apoptosis. Predicted to be involved in apoptotic process. Predicted to localize to cytoplasm. Is expressed in several structures, including gut; integument; liver; muscle cell; and solid lens vesicle. Human ortholog(s) of this gene implicated in ovarian carcinoma. Orthologous to human CASP6 (caspase 6).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With casp6a Human Ortholog
No data available
Associated With casp6a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR016129 Peptidase family C14A, His active site
Domain IPR001309 Peptidase C14, p20 domain
Domain IPR002138 Peptidase C14, caspase non-catalytic subunit p10
Domain IPR011600 Peptidase C14, caspase domain
Domain IPR015917 Peptidase C14A, caspase catalytic domain
Homologous_superfamily IPR029030 Caspase-like domain superfamily
Domain Details Per Protein
Protein Length Caspase-like domain superfamily Peptidase C14A, caspase catalytic domain Peptidase C14, caspase domain Peptidase C14, caspase non-catalytic subunit p10 Peptidase C14, p20 domain Peptidase family C14A, His active site
UniProtKB:F1R2P5
UniProtKB:Q52KK6 298
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA casp6-201 (1) Ensembl 1,578 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations