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ZIRC
ZFIN ID: ZDB-GENE-030820-2
Gene Name: signal transducer and activator of transcription 5a
Gene Symbol: stat5a
Sequence Ontology ID : SO:0000704

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Attributions

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Previous Names: stat5.1, stat5b, sb:eu615

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(Including Attributions)
Location: Chr: 3 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits DNA binding activity and DNA-binding transcription factor activity. Involved in several processes, including hemopoiesis; positive regulation of myeloid cell differentiation; and receptor  ...
GENE EXPRESSION
All Expression Data: 7 figures from 7 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2005 [eu615]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ihb393 Small Deletion Unknown Unknown CRISPR
ihb394 Small Deletion Unknown Frameshift, Premature Stop CRISPR
sa10709 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa19972 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa33126 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40029 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • tpl4Gt Transgenic Insertion Unknown Unknown DNA
    Targeting reagents:
    DISEASE ASSOCIATED WITH stat5a HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Leukemia, acute promyelocytic, somatic 102578
    Leukemia, acute promyelocytic, somatic 102578
    Growth hormone insensitivity with immunodeficiency 245590
    Growth hormone insensitivity with immunodeficiency 245590
    Leukemia, acute promyelocytic, somatic 102578
    Growth hormone insensitivity with immunodeficiency 245590
    Leukemia, acute promyelocytic, somatic 102578
    DISEASE ASSOCIATED WITH stat5a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process positive regulation of transcription by RNA polymerase II (more)
    Cellular Component cytoplasm (more)
    Molecular Function DNA binding (more)
    GO Terms (all 21)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA stat5a-202 (1) 880
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM stat5a No data available
    MARKER RELATIONSHIPS
    stat5aContained in: [BAC] CH73-271G12 (1) (order this), CH73-343F10 (1) (order this), DKEY-272F19 (1) (order this)
    stat5aEncodes: [EST] eu615 (1)
    [cDNA] MGC:193856 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_194387 (1) 2844bp
    Genomic RefSeq:NW_018394526 (1) Blast at MegaBLAST
    Polypeptide UniProtKB:C0SPC8 (1) 785aa
    Sequence Clusters UniGene:15667 (1)
    Sequence Information (all 37)
    ORTHOLOGY for stat5a (Chr: 3)
    CITATIONS (47)