Gene

cacna1ha

ID
ZDB-GENE-130103-1
Name
calcium channel, voltage-dependent, T type, alpha 1H subunit a
Symbol
cacna1ha Nomenclature History
Previous Names
  • sb:cb648
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have low voltage-gated calcium channel activity and voltage-gated sodium channel activity. Predicted to be involved in several processes, including calcium ion import; neuronal action potential; and positive regulation of calcium ion-dependent exocytosis. Predicted to localize to neuron projection and voltage-gated sodium channel complex. Is expressed in adaxial cell; diencephalon; heart; and retinal neural layer. Human ortholog(s) of this gene implicated in childhood absence epilepsy and primary hyperaldosteronism. Orthologous to human CACNA1H (calcium voltage-gated channel subunit alpha1 H).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cacna1ha Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Hyperaldosteronism, familial, type IV 617027
{Epilepsy, childhood absence, susceptibility to, 6} 611942
{Epilepsy, idiopathic generalized, susceptibility to, 6} 611942
Associated With cacna1ha Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR005821 Ion transport domain
Family IPR002077 Voltage-dependent calcium channel, alpha-1 subunit
Family IPR005445 Voltage-dependent calcium channel, T-type, alpha-1 subunit
Family IPR030162 Voltage-dependent calcium channel, T-type, alpha-1I subunit
Family IPR043203 Voltage-gated cation channel calcium and sodium
Homologous_superfamily IPR027359 Voltage-dependent channel domain superfamily
Domain Details Per Protein
Protein Length Ion transport domain Voltage-dependent calcium channel, alpha-1 subunit Voltage-dependent calcium channel, T-type, alpha-1I subunit Voltage-dependent calcium channel, T-type, alpha-1 subunit Voltage-dependent channel domain superfamily Voltage-gated cation channel calcium and sodium
UniProtKB:A0A2R8QRA4 685
UniProtKB:A0A2R8PWF8 367
UniProtKB:X1WBF7 2173
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations