ZFIN ID: ZDB-GENE-030725-2
Gene Name: growth hormone 1
Gene Symbol: gh1
Sequence Ontology ID : SO:0000704

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Previous Names: gh (1), ghl

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(Including Attributions)
Location: Chr: 3 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 51 figures from 29 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Adult (90d-730d, breeding adult)
  adenohypophyseal placode, adenohypophyseal placode somatotropin secreting cell, adenohypophysis, adenohypophysis somatotropin secreting cell (all 14) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
wp22e1 Point Mutation Exon 3 Premature Stop ENU
Targeting reagents: MO1-gh1 (1)
PHENOTYPE
Data: 6 figures from McMenamin et al., 2013
Observed in: adipose tissue, adipose tissue development, fat cell lipid droplet, fat cell (all 6) expand
DISEASE ASSOCIATED WITH gh1 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
isolated growth hormone deficiency type IA Growth hormone deficiency, isolated, type IA 262400
isolated growth hormone deficiency type IB Growth hormone deficiency, isolated, type IB 612781
isolated growth hormone deficiency type II Growth hormone deficiency, isolated, type II 173100
Kowarski syndrome 262650
GENE ONTOLOGY
Ontology GO Term
Biological Process adipose tissue development (more)
Cellular Component extracellular region (more)
Molecular Function growth hormone activity (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001400 (1)
  • InterPro:IPR009079 (1)
  • InterPro:IPR018116 (1)
  • InterPro:IPR034975 (1)
  • PROSITE:PS00266 (1)
  • PROSITE:PS00338 (1)
  • Pfam:PF00103 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA gh1-001 (1) 1197
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM gh1
    Tg(-2.2actb1:gh1,-2.2actb1:GFP)
    MARKER RELATIONSHIPS
    gh1Contained in: [BAC] DKEY-248K5 (order this)
    gh1Encodes: [cDNA] MGC:136327 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001020492 (1) 1210bp
    Genomic GenBank:BX005440 (1) 166695bp
    Select Tool
    Polypeptide UniProtKB:Q1JQ34 (1) 210aa
    Sequence Clusters UniGene:30452 (1)
    Sequence Information (all 14)
    OTHER gh1 GENE PAGES
  • Alliance (1)
  • Gene:407639 (1)
  • VEGA:OTTDARG00000019750 (1)
  • Ensembl(GRCz10):ENSDARG00000038185 (1)
  • ORTHOLOGY for gh1 (Chr: 3)
    CITATIONS (84)