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ZIRC
ZFIN ID: ZDB-GENE-030723-4
Gene Name: transforming growth factor, beta 3
Gene Symbol: tgfb3
Sequence Ontology ID : SO:0000704

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Previous Names: tgf beta 3 (1), wu:fc78g09, zgc:92058

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(Including Attributions)
Location: Chr: 17 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have cytokine activity and type II transforming growth factor beta receptor binding activity. Involved in hematopoietic stem cell differentiation; regulation of cartilage development;  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hu3526 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa1467 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa36544 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    DISEASE ASSOCIATED WITH tgfb3 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    arrhythmogenic right ventricular dysplasia 1 Arrhythmogenic right ventricular dysplasia 1 107970
    Loeys-Dietz syndrome 5 Loeys-Dietz syndrome 5 615582
    DISEASE ASSOCIATED WITH tgfb3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process hematopoietic stem cell differentiation (more)
    Cellular Component extracellular region (more)
    Molecular Function growth factor activity (more)
    GO Terms (all 18)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    ncRNA tgfb3-002 (1) 465
    mRNA tgfb3-201 (1) 2073
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM tgfb3 No data available
    MARKER RELATIONSHIPS
    tgfb3Contained in: [BAC] CH73-60D15 (1) (order this)
    [Fosmid] CH1073-297M1 (1) (order this)
    tgfb3Encodes: [EST] fc78g09 (1), IMAGE:7150374 (1) (order this), tgf_beta_3 (1)
    [cDNA] MGC:92058 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_194386 (1) 2035bp
    Genomic GenBank:FP325132 (1) 35292bp
    Select Tool
    Polypeptide UniProtKB:Q66I23 (1) 410aa
    Sequence Clusters UniGene:116110 (1)
    Sequence Information (all 19)
    ORTHOLOGY for tgfb3 (Chr: 17)
    CITATIONS (59)