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ZIRC
ZFIN ID: ZDB-GENE-030723-2
Gene Name: nuclear factor, erythroid 2-like 2a
Gene Symbol: nfe2l2a
Sequence Ontology ID : SO:0000704

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Previous Names: nfe2l2, Nrf2 (1), Nrf2a (1), wu:fc15g09 (1), wu:fj67e03 (1)

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(Including Attributions)
Location: Chr: 9 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits protein heterodimerization activity and transcription regulatory region sequence-specific DNA binding activity. Contributes to DNA-binding transcription factor activity. Involved in several  ...
GENE EXPRESSION
All Expression Data: 9 figures from 8 publications
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
fh318 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • fh319 Point Mutation Unknown Unknown ENU
    ihb247 Indel Exon 2 Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • ihb256 Small Deletion Exon 4 Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • la026758Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la026760Tg Transgenic Insertion Unknown Unknown DNA
    nfe2l2a_unrecovered Point Mutation Unknown Unknown ENU
    sa21416 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    DISEASE ASSOCIATED WITH nfe2l2a HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Immunodeficiency, developmental delay, and hypohomocysteinemia 617744
    Immunodeficiency, developmental delay, and hypohomocysteinemia 617744
    DISEASE ASSOCIATED WITH nfe2l2a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of transcription, DNA-templated (more)
    Cellular Component cytoplasm (more)
    Molecular Function DNA binding (more)
    GO Terms (all 14)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA nfe2l2a-201 (1) 4739
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM nfe2l2a No data available
    MARKER RELATIONSHIPS
    nfe2l2aContained in: [BAC] CH211-230E14 (1) (order this)
    nfe2l2aEncodes: [EST] fc15g09, fj67e03
    [cDNA] MGC:56001 (1) (order this), MGC:174016 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_182889 (1) 2194bp
    Genomic GenBank:CR848724 (1) 154185bp
    Select Tool
    Polypeptide UniProtKB:A7YYH1 (1) 586aa
    Sequence Clusters UniGene:155361 (1)
    Sequence Information (all 22)
    ORTHOLOGY for nfe2l2a (Chr: 9)
    CITATIONS (119)