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Gene

slit1b

ID
ZDB-GENE-030722-4
Name
slit homolog 1b (Drosophila)
Symbol
slit1b Nomenclature History
Previous Names
  • chunp9742
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Predicted to enable calcium ion binding activity. Acts upstream of or within cranial nerve morphogenesis. Predicted to be located in extracellular region. Predicted to be active in plasma membrane. Is expressed in central nervous system; forebrain; hindbrain; hindbrain nucleus; and retinal inner nuclear layer. Orthologous to human SLIT1 (slit guidance ligand 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 7 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Zecca et al., 2015
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With slit1b Human Ortholog
No data available
Associated With slit1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR013032 EGF-like, conserved site
Conserved_site IPR018097 EGF-like calcium-binding, conserved site
Domain IPR000372 Leucine-rich repeat N-terminal domain
Domain IPR000483 Cysteine-rich flanking region, C-terminal
Domain IPR000742 EGF-like domain
Domain IPR001791 Laminin G domain
Domain IPR001881 EGF-like calcium-binding domain
Domain IPR006207 Cystine knot, C-terminal
Homologous_superfamily IPR009030 Growth factor receptor cysteine-rich domain superfamily
Homologous_superfamily IPR013320 Concanavalin A-like lectin/glucanase domain superfamily
Homologous_superfamily IPR032675 Leucine-rich repeat domain superfamily
PTM IPR000152 EGF-type aspartate/asparagine hydroxylation site
Repeat IPR001611 Leucine-rich repeat
Repeat IPR003591 Leucine-rich repeat, typical subtype
Domain Details Per Protein
Protein Length Concanavalin A-like lectin/glucanase domain superfamily Cysteine-rich flanking region, C-terminal Cystine knot, C-terminal EGF-like calcium-binding, conserved site EGF-like calcium-binding domain EGF-like, conserved site EGF-like domain EGF-type aspartate/asparagine hydroxylation site Growth factor receptor cysteine-rich domain superfamily Laminin G domain Leucine-rich repeat Leucine-rich repeat domain superfamily Leucine-rich repeat N-terminal domain Leucine-rich repeat, typical subtype
UniProtKB:A0A0R4IAZ7 813
UniProtKB:Q3Y6S4 1532
UniProtKB:A0A0R4IU60 1531
UniProtKB:A0A2R8QDY6 1532
UniProtKB:A0A0R4IFC7 640
UniProtKB:B0CM06 1532
UniProtKB:B3DJQ5 1531
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations