ZFIN ID: ZDB-GENE-030717-4
Gene Name: CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
Gene Symbol: cds2    Nomenclature History

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Previous Name: zgc:66134

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have phosphatidate cytidylyltransferase activity. Involved in angiogenesis; positive regulation of ERK1 and ERK2 cascade; and positive regulation of vascular endothelial growth factor signaling pathway. Predicted to localize to endoplasmic reticulum membrane. Is expressed in trunk vasculature. Orthologous to human CDS2 (CDP-diacylglycerol synthase 2).
Genome Resources: Alliance (1),  Gene:394161 (1),  Ensembl(GRCz11):ENSDARG00000035577 (2)
GENE EXPRESSION
All Expression Data: 8 figures from 3 publications
Directly Submitted Expression Data: 6 figures (6 images) from Thisse et al., 2004 [MGC:66134]
  1 figure (1 image) from Thisse et al., 2005 [eu66]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
cas008 Small Deletion Unknown Unknown CRISPR
la011199Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa31426 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa38461 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • y25 Point Mutation Unknown Premature Stop ENU
    y54 Point Mutation Unknown Premature Stop ENU
    zy14 Point Mutation Unknown Premature Stop ENU
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-cds2 1
    MO2-cds2 N/A 2
    DISEASE ASSOCIATED WITH cds2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH cds2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process angiogenesis (more)
    Cellular Component integral component of membrane (more)
    Molecular Function nucleotidyltransferase activity (more)
    GO Terms (all 13)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cds2-201 (1)    Ensembl 2822
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cds2 No data available
    MARKER RELATIONSHIPS
    cds2 Contained in: [BAC] DKEY-13N15 (1) (order this)
    cds2 Encodes: [EST] eu66 (1)
    [cDNA] MGC:55509 (1), MGC:66134 (1), MGC:192424 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_201186 (1) 2843 nt
    Genomic GenBank:BX470224 (1) 244492 nt Blast at MegaBLAST
    Polypeptide UniProtKB:A2BGK0 (1) 444 aa
    Sequence Information (all 17)
    ORTHOLOGY for cds2 ( Chr: 5 )
    CITATIONS (32)