Gene

slc26a2

ID
ZDB-GENE-030717-3
Name
solute carrier family 26 member 2
Symbol
slc26a2 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to have anion transmembrane transporter activity. Involved in sensory organ development; sensory perception of sound; and swimming behavior. Predicted to localize to integral component of plasma membrane. Is expressed in lateral line primordium; midbrain; otic vesicle; pectoral fin bud; and pronephric duct. Human ortholog(s) of this gene implicated in bone disease (multiple). Orthologous to human SLC26A2 (solute carrier family 26 member 2).
Genome Resources
Note
None
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from Liu et al., 2015
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With slc26a2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
achondrogenesis type IB Alliance Achondrogenesis Ib 600972
atelosteogenesis Alliance Atelosteogenesis, type II 256050
atelosteogenesis Alliance De la Chapelle dysplasia 256050
diastrophic dysplasia Alliance Diastrophic dysplasia 222600
diastrophic dysplasia Alliance Diastrophic dysplasia, broad bone-platyspondylic variant 222600
multiple epiphyseal dysplasia 4 Alliance Epiphyseal dysplasia, multiple, 4 226900
Associated With slc26a2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018045 Sulphate anion transporter, conserved site
Domain IPR002645 STAS domain
Domain IPR011547 SLC26A/SulP transporter domain
Family IPR001902 SLC26A/SulP transporter
Family IPR030280 Solute carrier family 26 member 2
Homologous_superfamily IPR036513 STAS domain superfamily
Domain Details Per Protein
Protein Length SLC26A/SulP transporter SLC26A/SulP transporter domain Solute carrier family 26 member 2 STAS domain STAS domain superfamily Sulphate anion transporter, conserved site
UniProtKB:E7F9I7 699
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations