ZFIN ID: ZDB-GENE-030717-2
Gene Name: wingless-type MMTV integration site family, member 2Ba
Gene Symbol: wnt2ba    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to have cytokine activity and frizzled binding activity. Involved in embryonic pectoral fin morphogenesis and sensory epithelium regeneration. Predicted to localize to extracellular space. Is expressed in brain; immature eye; intermediate mesoderm; pectoral fin field; and pronephros. Human ortholog(s) of this gene implicated in congenital diarrhea. Orthologous to human WNT2B (Wnt family member 2B).
Genome Resources: Alliance (1),  Gene:359837 (1),  Ensembl(GRCz11):ENSDARG00000005050 (1)
GENE EXPRESSION
All Expression Data: 11 figures from 8 publications
Wild-type Stages, Structures: Gastrula:Shield (6.0h-8.0h) to Pharyngula:Prim-5 (24.0h-30.0h)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa16775 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-wnt2ba N/A 1
    MO2-wnt2ba N/A 2
    MO3-wnt2ba N/A 1
    PHENOTYPE
    Data: 3 figures from 3 publications
    Observed in:
    DISEASE ASSOCIATED WITH wnt2ba HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Diarrhea 9 618168
    DISEASE ASSOCIATED WITH wnt2ba VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process embryonic pectoral fin morphogenesis (more)
    Cellular Component extracellular region (more)
    Molecular Function signaling receptor binding (more)
    GO Terms (all 14)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA wnt2ba-201 (1)    Ensembl 1771
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM wnt2ba No data available
    MARKER RELATIONSHIPS
    wnt2ba Contained in: [BAC] DKEY-166J19 (1) (order this)
    wnt2ba Encodes: [cDNA] MGC:193521 (1), MGC:193522 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_182876 (1) 1794 nt
    Genomic GenBank:CR382321 (1) 212455 nt Blast at MegaBLAST
    Polypeptide UniProtKB:B3DFK5 (1) 387 aa
    Sequence Information (all 16)
    ORTHOLOGY for wnt2ba ( Chr: 6 )
    CITATIONS (44)