ZFIN ID: ZDB-GENE-030717-1
Gene Name: rho/rac guanine nucleotide exchange factor (GEF) 2
Gene Symbol: arhgef2
Sequence Ontology ID : SO:0000704

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Previous Names: fj11d04, si:ch211-198o19.3, wu:fj11d04 (1)

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(Including Attributions)
Location: Chr: 16 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have Rho guanyl-nucleotide exchange factor activity and metal ion binding activity; predicted to be involved in intracellular signal transduction and regulation of Rho protein signal  ...
GENE EXPRESSION
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa22746 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa22747 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH arhgef2 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    neurodevelopmental disorder with midbrain and hindbrain malformations ?Neurodevelopmental disorder with midbrain and hindbrain malformations 617523
    DISEASE ASSOCIATED WITH arhgef2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process intracellular signal transduction (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000219 (1)
  • InterPro:IPR001849 (1)
  • InterPro:IPR002219 (1)
  • InterPro:IPR011993 (1)
  • InterPro:IPR035899 (1)
  • PROSITE:PS00479 (1)
  • PROSITE:PS50003 (1)
  • PROSITE:PS50010 (1)
  • PROSITE:PS50081 (1)
  • Pfam:PF00130 (1)
  • Pfam:PF00621 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA arhgef2-201 (1) 3993
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM arhgef2 No data available
    MARKER RELATIONSHIPS
    arhgef2Contained in: [BAC] CH211-198O19 (1) (order this)
    arhgef2Encodes: [EST] fj11d04
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_684678 (1) 3768bp
    Genomic GenBank:AL845419 (1) 176379bp
    Select Tool
    Polypeptide UniProtKB:A0A2R8Q3N3 (1) 902aa
    Sequence Clusters UniGene:122291 (1)
    Sequence Information (all 18)
    OTHER arhgef2 GENE PAGES
  • Alliance (1)
  • Gene:561276 (1)
  • VEGA:OTTDARG00000034028 (1)
  • Ensembl(GRCz11):ENSDARG00000075819 (2)
  • ORTHOLOGY for arhgef2 (Chr: 16)
    CITATIONS (15)