Gene

tfpia

ID
ZDB-GENE-030711-1
Name
tissue factor pathway inhibitor a
Symbol
tfpia Nomenclature History
Previous Names
  • tfpib
  • si:dz44f8.1
  • wu:fb92g01
  • zgc:152844
  • zgc:158592
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to have serine-type endopeptidase inhibitor activity. Predicted to be involved in blood coagulation and negative regulation of peptidase activity. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in several diseases, including factor VIII deficiency; osteonecrosis; thrombophilia (multiple); toxic shock syndrome; and transient cerebral ischemia. Is expressed in caudal fin skeleton. Orthologous to human TFPI (tissue factor pathway inhibitor).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tfpia Human Ortholog
No data available
Associated With tfpia Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR020901 Proteinase inhibitor I2, Kunitz, conserved site
Domain IPR002223 Pancreatic trypsin inhibitor Kunitz domain
Family IPR008296 Tissue factor pathway inhibitor-like
Homologous_superfamily IPR036880 Pancreatic trypsin inhibitor Kunitz domain superfamily
Domain Details Per Protein
Protein Length Pancreatic trypsin inhibitor Kunitz domain Pancreatic trypsin inhibitor Kunitz domain superfamily Proteinase inhibitor I2, Kunitz, conserved site Tissue factor pathway inhibitor-like
UniProtKB:Q05AN9 279
UniProtKB:E7EXD1 278
UniProtKB:A2RV09 278
UniProtKB:Q504K2 292
UniProtKB:B0S6C1 279
UniProtKB:Q8AYE1 277
UniProtKB:Q7ZZ42 251
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations