ZFIN ID: ZDB-GENE-030708-1
Gene Name: fibroblast growth factor 24
Gene Symbol: fgf24    Nomenclature History

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Previous Names: wfgf (2), ika, ikarus, si:zc207o21.1, wound fgf (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 14 Mapping Details/Browsers
Description: Predicted to have growth factor activity. Involved in several processes, including animal organ development; appendage morphogenesis; and negative regulation of endodermal cell fate specification. Is expressed in several structures, including digestive system; fin bud; mesenchyme; mesoderm; and sensory system.
Genome Resources: Alliance (1),  Gene:359831 (1),  Ensembl(GRCz11):ENSDARG00000037677 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
t22030 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tm127c Point Mutation Unknown Missense ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • uc47 Insertion Exon 3 Frameshift, Premature Stop CRISPR
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-fgf24 1
    MO1-fgf24 N/A 8
    MO2-fgf24 N/A 9
    DISEASE ASSOCIATED WITH fgf24 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH fgf24 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process ectodermal placode development (more)
    Molecular Function growth factor activity (more)
    GO Terms (all 12)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Family IPR002209 Fibroblast growth factor family
    Homologous_superfamily IPR008996 Cytokine IL1/FGF
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA fgf24-201 (1)    Ensembl 2376
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM fgf24
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg1BAC(fgf24:GFP) fgf24 GFP Danio rerio 1 2
    Tg2BAC(fgf24:GFP) fgf24 GFP Danio rerio 1 3
    TgBAC(fgf24:EGFP) fgf24 EGFP Danio rerio 1 2
    MARKER RELATIONSHIPS
    fgf24 Contained in: [BAC] CH211-163F17 (1), CH211-207O21 (1)
    fgf24 Contains: [STS] unp1106
    fgf24 Encodes: [EST] eu782 (1)
    [cDNA] MGC:152742 (1), MGC:192505 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_182871 (1) 1378 bp
    Genomic GenBank:AL831789 (1) 217649 bp Blast at MegaBLAST
    Polypeptide UniProtKB:Q0IIQ7 (1) 208 aa
    Sequence Clusters UniGene:82992 (1)
    Sequence Information (all 22)
    ORTHOLOGY for fgf24 ( Chr: 14 )
    CITATIONS (89)