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ZIRC
ZFIN ID: ZDB-GENE-030619-14
Gene Name: polo-like kinase 4 (Drosophila)
Gene Symbol: plk4
Sequence Ontology ID : SO:0000704

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Attributions

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Previous Names: stk18 (1), wu:fi33g07

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(Including Attributions)
Location: Chr: 17 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have protein serine/threonine kinase activity; involved in centriole assembly, cilium assembly, and developmental growth; predicted to localize to the centriole, deuterosome, and  ...
GENE EXPRESSION
All Expression Data: 6 figures from 4 publications
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Targeting reagents:
DISEASE ASSOCIATED WITH plk4 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
microcephaly and chorioretinopathy 2 Microcephaly and chorioretinopathy, autosomal recessive, 2 616171
DISEASE ASSOCIATED WITH plk4 VIA EXPERIMENTAL MODELS
Human Disease Fish Conditions Citations
ciliopathy AB/TU + MO2-plk4 + MO3-plk4 standard conditions Martin et al., 2014
GENE ONTOLOGY
Ontology GO Term
Biological Process centriole assembly (more)
Cellular Component centriole (more)
Molecular Function protein serine/threonine kinase activity (more)
GO Terms (all 19)
TRANSCRIPTS
Type Name Length (bp) Analysis
mRNA plk4-201 (1) 3297
GENE PRODUCT DESCRIPTION
INTERACTIONS AND PATHWAYS
SignaFish
ANTIBODIESNo data available
PLASMIDSNo data available
CONSTRUCTS WITH SEQUENCES FROM plk4 No data available
MARKER RELATIONSHIPS
plk4Contained in: [BAC] DKEY-21A6 (1) (order this)
plk4Encodes: [EST] fi33g07
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001118892 (1) 3299bp
Genomic GenBank:CR405694 (1) 207188bp Blast at MegaBLAST
Polypeptide UniProtKB:F1RB74 (1) 941aa
Sequence Clusters UniGene:80660 (1)
Sequence Information (all 15)
ORTHOLOGY for plk4 (Chr: 17)
CITATIONS (23)