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General Information
ZIRC
ZFIN ID: ZDB-GENE-030618-1
Gene Name: transforming growth factor, beta 1a
Gene Symbol: tgfb1a
Sequence Ontology ID : SO:0000704

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Previous Names: tgfb1 (1), ai39657, wu:fb13a07 (1), xx:ai39657

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(Including Attributions)
Location: Chr: 15 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have cytokine activity and type II transforming growth factor beta receptor binding activity. Involved in hematopoietic stem cell differentiation; otolith development; and posterior  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa16296 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39023 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39024 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa42471 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • tsu1td Small Deletion Exon 1 Frameshift, Premature Stop TALEN
    tsu5td Small Deletion Exon 1 Frameshift, Premature Stop TALEN
  • China Zebrafish Resource Center (CZRC) (order this)
  • tsu8td Small Deletion Exon 1 Frameshift, Premature Stop TALEN
    Targeting reagents:
    DISEASE ASSOCIATED WITH tgfb1a HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Camurati-Engelmann disease Camurati-Engelmann disease 131300
    cystic fibrosis {Cystic fibrosis lung disease, modifier of} 219700
    Inflammatory bowel disease, immunodeficiency, and encephalopathy 618213
    Inflammatory bowel disease, immunodeficiency, and encephalopathy 618213
    DISEASE ASSOCIATED WITH tgfb1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process hematopoietic stem cell differentiation (more)
    Cellular Component extracellular region (more)
    Molecular Function growth factor activity (more)
    GO Terms (all 21)
    TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM tgfb1a
    MARKER RELATIONSHIPS
    tgfb1aEncodes: [EST] eu837 (1), fb13a07
    [cDNA] MGC:194011 (1) (order this), MGC:194018 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_182873 (1)
    Genomic GenBank:CABZ01086045 (1) 27539bp
    Select Tool
    Polypeptide UniProtKB:F1R741 (1) 377aa
    Sequence Clusters UniGene:76626 (1)
    Sequence Information (all 22)
    OTHER tgfb1a GENE PAGES
  • Alliance (1)
  • Gene:359834 (1)
  • Ensembl(GRCz11):ENSDARG00000041502 (2)
  • ORTHOLOGY for tgfb1a (Chr: 15)
    CITATIONS (114)