Gene

ube2a

ID
ZDB-GENE-030616-72
Name
ubiquitin-conjugating enzyme E2A (RAD6 homolog)
Symbol
ube2a Nomenclature History
Previous Names
  • mp:zf637-2-000771
  • si:bz46j2.4
  • wu:fa01h11
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to have ubiquitin conjugating enzyme activity. Predicted to be involved in DNA repair; proteasome-mediated ubiquitin-dependent protein catabolic process; and protein ubiquitination. Predicted to localize to HULC complex and nuclear chromatin. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability Nascimento type. Orthologous to human UBE2A (ubiquitin conjugating enzyme E2 A).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ube2a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
syndromic X-linked intellectual disability Nascimento type Alliance Intellectual developmental disorder, X-linked syndromic, Nascimento type 300860
Associated With ube2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR023313 Ubiquitin-conjugating enzyme, active site
Domain IPR000608 Ubiquitin-conjugating enzyme E2
Homologous_superfamily IPR016135 Ubiquitin-conjugating enzyme/RWD-like
Domain Details Per Protein
Protein Length Ubiquitin-conjugating enzyme, active site Ubiquitin-conjugating enzyme E2 Ubiquitin-conjugating enzyme/RWD-like
UniProtKB:Q789K9 152
UniProtKB:A0A0R4IFH4 119
UniProtKB:A0A140LGJ3 119
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations