Gene

ube2a

ID
ZDB-GENE-030616-72
Name
ubiquitin-conjugating enzyme E2A (RAD6 homolog)
Symbol
ube2a Nomenclature History
Previous Names
  • mp:zf637-2-000771
  • si:bz46j2.4
  • wu:fa01h11
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to have ubiquitin conjugating enzyme activity. Predicted to be involved in DNA repair; proteasome-mediated ubiquitin-dependent protein catabolic process; and protein ubiquitination. Predicted to localize to HULC complex and nuclear chromatin. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability Nascimento type. Orthologous to human UBE2A (ubiquitin conjugating enzyme E2 A).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ube2a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
syndromic X-linked intellectual disability Nascimento type Alliance Mental retardation, X-linked syndromic, Nascimento-type 300860
Associated With ube2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR023313 Ubiquitin-conjugating enzyme, active site
Domain IPR000608 Ubiquitin-conjugating enzyme E2
Homologous_superfamily IPR016135 Ubiquitin-conjugating enzyme/RWD-like
Domain Details Per Protein
Protein Length Ubiquitin-conjugating enzyme, active site Ubiquitin-conjugating enzyme E2 Ubiquitin-conjugating enzyme/RWD-like
UniProtKB:Q789K9 152
UniProtKB:A0A0R4IFH4 119
UniProtKB:A0A140LGJ3 119
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations