Gene

dnah6

ID
ZDB-GENE-030616-623
Name
dynein, axonemal, heavy chain 6
Symbol
dnah6 Nomenclature History
Previous Names
  • dnah7l
  • si:zc220f6.1
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to have ATP-dependent microtubule motor activity, minus-end-directed; dynein intermediate chain binding activity; and dynein light intermediate chain binding activity. Involved in determination of heart left/right asymmetry and epithelial cilium movement involved in determination of left/right asymmetry. Predicted to localize to dynein complex. Is expressed in Kupffer's vesicle and testis. Orthologous to human DNAH6 (dynein axonemal heavy chain 6).
Genome Resources
Note
None
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Li et al., 2016
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dnah6 Human Ortholog
No data available
Associated With dnah6 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003593 AAA+ ATPase domain
Domain IPR004273 Dynein heavy chain region D6 P-loop domain
Domain IPR013602 Dynein heavy chain, domain-2
Domain IPR024317 Dynein heavy chain, AAA module D4
Domain IPR024743 Dynein heavy chain, coiled coil stalk
Domain IPR035699 Dynein heavy chain, hydrolytic ATP-binding dynein motor region
Domain IPR035706 Dynein heavy chain, ATP-binding dynein motor region
Domain IPR041228 Dynein heavy chain, C-terminal domain
Domain IPR041466 Dynein heavy chain, AAA 5 extension domain
Domain IPR041589 Dynein heavy chain 3, AAA+ lid domain
Domain IPR041658 Dynein heavy chain AAA lid domain
Family IPR026983 Dynein heavy chain
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR042219 Dynein heavy chain AAA lid domain superfamily
Homologous_superfamily IPR042222 Dynein heavy chain, domain 2, N-terminal
Homologous_superfamily IPR042228 Dynein heavy chain, domain 2, C-terminal
Homologous_superfamily IPR043157 Dynein heavy chain, AAA1 domain, small subdomain
Domain Details Per Protein
Protein Length AAA+ ATPase domain Dynein heavy chain Dynein heavy chain 3, AAA+ lid domain Dynein heavy chain, AAA1 domain, small subdomain Dynein heavy chain, AAA 5 extension domain Dynein heavy chain AAA lid domain Dynein heavy chain AAA lid domain superfamily Dynein heavy chain, AAA module D4 Dynein heavy chain, ATP-binding dynein motor region Dynein heavy chain, coiled coil stalk Dynein heavy chain, C-terminal domain Dynein heavy chain, domain-2 Dynein heavy chain, domain 2, C-terminal Dynein heavy chain, domain 2, N-terminal Dynein heavy chain, hydrolytic ATP-binding dynein motor region Dynein heavy chain region D6 P-loop domain P-loop containing nucleoside triphosphate hydrolase
UniProtKB:E9QEF8 84
UniProtKB:E9QH47 3966
UniProtKB:F1Q6J7 4163
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations