ZFIN ID: ZDB-GENE-030616-608
Gene Name: isoleucyl-tRNA synthetase 2, mitochondrial
Gene Symbol: iars2    Nomenclature History

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Previous Names: si:ch211-214p16.3 (1), si:zc214p16.3

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 17 Mapping Details/Browsers
Description: Predicted to have isoleucine-tRNA ligase activity. Predicted to be involved in isoleucyl-tRNA aminoacylation and mitochondrial translation. Predicted to localize to mitochondrion. Orthologous to human IARS2 (isoleucyl-tRNA synthetase 2, mitochondrial).
Genome Resources: Alliance (1),  Gene:100001219 (1),  Ensembl(GRCz11):ENSDARG00000044134 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7148330]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
PHENOTYPE No data available
DISEASE ASSOCIATED WITH iars2 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
?Cataracts, growth hormone deficiency, sensory neuropathy, sensorineural hearing loss, and skeletal dysplasia 616007
DISEASE ASSOCIATED WITH iars2 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process isoleucyl-tRNA aminoacylation (more)
Cellular Component mitochondrion (more)
Molecular Function aminoacyl-tRNA editing activity (more)
GO Terms (all 12)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA iars2-201 (1)    Ensembl 8372
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM iars2 No data available
MARKER RELATIONSHIPS
iars2 Contained in: [BAC] CH73-374A13 (1), CH211-214P16 (1)
iars2 Encodes: [EST] IMAGE:7148330 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001163798 (1) 3061 nt
Genomic GenBank:FP015823 (1) 103711 nt
Select Tool
Polypeptide UniProtKB:F1QUQ0 (1) 983 aa
Sequence Information (all 11)
ORTHOLOGY for iars2 ( Chr: 17 )
CITATIONS (25)