Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-030616-571
Gene Name: autism susceptibility candidate 2
Gene Symbol: auts2
Previous Names: si:ch211-103d22.3, si:zc103d22.3, wu:fj83b10
Nomenclature History
GENE EXPRESSION
All Expression Data: Fig. S1 from Oksenberg et al., 2013
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
  brain, caudal peduncle, eye, forebrain (all 8) expand
MUTANTS AND TARGETED KNOCKDOWNS
Knockdown reagents: MO1-auts2 (1), MO2-auts2 (1), MO3-auts2 (1), MO4-auts2 (1)
PHENOTYPE
Data: 7 figures from 2 publications
Observed in: apoptotic process, cell proliferation in forebrain, cell proliferation in hindbrain, cell proliferation in midbrain (all 22) expand
GENE ONTOLOGY
Ontology GO Term
Biological Process embryo development (more)
GO Terms (all 4)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR023246 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA auts2-001 (1) 4214
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM auts2 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    auts2 Contained in: [BAC] CH211-59F17 (1) (order this), CH211-103D22 (1) (order this)
    auts2 Encodes: [EST] fj83b10
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_002663553 (1) 6067 bp
    Genomic GenBank:AL929319 (1) 194614 bp
    Select Tool
    Polypeptide UniProtKB:F1QRM5 (1) 1019 aa
    Sequence Clusters UniGene:76757 (1)
    Sequence Information (all 22)
    OTHER auts2 GENE PAGES
  • Gene:368890 (1)
  • VEGA:OTTDARG00000023715 (1)
  • Ensembl(Zv9):ENSDARG00000056427 (1)
  • MAPPING INFORMATION
    Chr: 10 Details
    ORTHOLOGY
      Evidence
    Species Symbol Chromosome (Position) Accession # AA
    Zebrafish auts2 10  
    Human AUTS2 7 (7q11.22)
  • OMIM:607270
  • Gene:26053
  • CITATIONS (10)