ZFIN ID: ZDB-GENE-030616-571
Gene Name: autism susceptibility candidate 2a
Gene Symbol: auts2a

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Previous Names: auts2, si:ch211-103d22.3, si:zc103d22.3, wu:fj83b10

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(Including Attributions)
Location: Chr: 10 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: Fig. S1 from Oksenberg et al., 2013
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
  brain, caudal peduncle, eye, forebrain (all 8) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa21753 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents: MO1-auts2a (1), MO2-auts2a (1), MO3-auts2a (1), MO4-auts2a (1)
    PHENOTYPE
    Data: 7 figures from 2 publications
    Observed in: apoptotic process, cell proliferation in forebrain, cell proliferation in hindbrain, cell proliferation in midbrain (all 22) expand
    DISEASE ASSOCIATED WITH auts2a HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    autosomal dominant non-syndromic intellectual disability Mental retardation, autosomal dominant 26 615834
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process chordate embryonic development (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR023246 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA auts2a-001 (1) 4214
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM auts2a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    auts2aContained in: [BAC] CH211-59F17 (1) (order this), CH211-103D22 (1) (order this)
    auts2aEncodes: [EST] fj83b10
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_009305336 (1) 5778bp
    Genomic GenBank:AL929319 (1) 194614bp
    Select Tool
    Polypeptide UniProtKB:F1QRM5 (1) 1082aa
    Sequence Clusters UniGene:155660 (1)
    Sequence Information (all 31)
    OTHER auts2a GENE PAGES
  • Gene:368890 (1)
  • VEGA:OTTDARG00000023715 (1)
  • Ensembl(GRCz10):ENSDARG00000056427 (1)
  • ORTHOLOGY for auts2a (Chr: 10)
    Species Symbol Chromosome Accession # Evidence
    Human AUTS2 7
  • Gene:26053
  • OMIM:607270
  • HGNC:14262
  • Amino acid sequence comparison (1)
    Nucleotide sequence comparison (1)
    Download Curated Orthology
    CITATIONS (12)