ZFIN ID: ZDB-GENE-030616-571
Gene Name: autism susceptibility candidate 2a
Gene Symbol: auts2a
Previous Names: auts2, si:ch211-103d22.3, si:zc103d22.3, wu:fj83b10
Location: Chr: 10   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: Fig. S1 from Oksenberg et al., 2013
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
  brain, caudal peduncle, eye, forebrain (all 8) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Targeting reagents: MO1-auts2a (1), MO2-auts2a (1), MO3-auts2a (1), MO4-auts2a (1)
PHENOTYPE
Data: 7 figures from 2 publications
Observed in: apoptotic process, cell proliferation in forebrain, cell proliferation in hindbrain, cell proliferation in midbrain (all 22) expand
DISEASE ASSOCIATED WITH auts2a HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
autosomal dominant non-syndromic intellectual disability Mental retardation, autosomal dominant 26 615834
GENE ONTOLOGY
Ontology GO Term
Biological Process chordate embryonic development (more)
GO Terms (all 4)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR023246 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA auts2a-001 (1) 4214
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM auts2a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    auts2a Contained in: [BAC] CH211-59F17 (1) (order this), CH211-103D22 (1) (order this)
    auts2a Encodes: [EST] fj83b10
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_009305336 (1) 5778 bp
    Genomic GenBank:AL929319 (1) 194614 bp
    Select Tool
    Polypeptide UniProtKB:F1QRM5 (1) 1019 aa
    Sequence Clusters UniGene:155660 (1)
    Sequence Information (all 32)
    OTHER auts2a GENE PAGES
  • Gene:368890 (1)
  • VEGA:OTTDARG00000023715 (1)
  • Ensembl(Zv9):ENSDARG00000056427 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA NT
    Zebrafish auts2a 10  
    Human AUTS2 7 (7q11.22)
  • OMIM:607270
  • Gene:26053
  • Orthology Details
    CITATIONS (11)