ZFIN ID: ZDB-GENE-030616-53
Gene Name: glutamate receptor, ionotropic, AMPA 3b
Gene Symbol: gria3b    Nomenclature History

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Previous Names: glur3b, gria3.2, gria3, zfGRIA3[b] (1), si:bz1o18.1, si:zc140k5.3

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 14 Mapping Details/Browsers
Description: Predicted to have AMPA glutamate receptor activity. Predicted to be involved in ion transport. Predicted to localize to the AMPA glutamate receptor complex. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability 94. Is expressed in nervous system. Orthologous to human GRIA3 (glutamate ionotropic receptor AMPA type subunit 3).
Genome Resources: Alliance (1),  Gene:368416 (1),  Ensembl(GRCz11):ENSDARG00000037498 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la011015Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la012477Tg Transgenic Insertion Unknown Unknown DNA
    la018793Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la018794Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la018795Tg Transgenic Insertion Unknown Unknown DNA
    sa6340 Point Mutation Unknown Premature Stop ENU
    sa22436 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa35652 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa42362 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH gria3b HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    syndromic X-linked intellectual disability 94 Alliance Mental retardation, X-linked 94 300699
    DISEASE ASSOCIATED WITH gria3b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process ion transport (more)
    Cellular Component cell junction (more)
    Molecular Function ion channel activity (more)
    GO Terms (all 19)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR001320 Ionotropic glutamate receptor
    Family IPR001508 Ionotropic glutamate receptor, metazoa
    Domain IPR001638 Solute-binding protein family 3/N-terminal domain of MltF
    Domain IPR001828 Receptor, ligand binding region
    Domain IPR019594 Ionotropic glutamate receptor, L-glutamate and glycine-binding domain
    Homologous_superfamily IPR028082 Periplasmic binding protein-like I
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA gria3b-202 (1)    Ensembl 4681
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM gria3b No data available
    MARKER RELATIONSHIPS
    gria3b Contained in: [BAC] CH211-140K5, CH211-231H1, DKEY-41K7 (1) (order this), DKEYP-4H2 (1), RP71-1O18 (1)
    gria3b Encodes: [EST] eu751 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_198360 (1) 2708 bp
    Genomic GenBank:BX511226 (1) 252757 bp Blast at MegaBLAST
    Polypeptide UniProtKB:A0A286Y9Q6 (1) 883 aa
    Sequence Information (all 32)
    ORTHOLOGY for gria3b ( Chr: 14 )
    CITATIONS (33)