Gene

pms1

ID
ZDB-GENE-030616-528
Name
PMS1 homolog 1, mismatch repair system component
Symbol
pms1 Nomenclature History
Previous Names
  • si:dz164h20.2
  • si:dz72b14.2
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to have ATPase activity. Predicted to be involved in mismatch repair. Predicted to localize to MutLalpha complex. Human ortholog(s) of this gene implicated in Lynch syndrome; dermatomyositis; and pancreatic ductal carcinoma. Orthologous to human PMS1 (PMS1 homolog 1, mismatch repair system component).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pms1 Human Ortholog
No data available
Associated With pms1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR014762 DNA mismatch repair, conserved site
Domain IPR002099 DNA mismatch repair protein family, N-terminal
Domain IPR009071 High mobility group box domain
Domain IPR013507 DNA mismatch repair protein, S5 domain 2-like
Family IPR038973 DNA mismatch repair protein MutL/Mlh/Pms
Homologous_superfamily IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup
Homologous_superfamily IPR020568 Ribosomal protein S5 domain 2-type fold
Homologous_superfamily IPR036890 Histidine kinase/HSP90-like ATPase superfamily
Homologous_superfamily IPR036910 High mobility group box domain superfamily
Domain Details Per Protein
Protein Length DNA mismatch repair, conserved site DNA mismatch repair protein family, N-terminal DNA mismatch repair protein MutL/Mlh/Pms DNA mismatch repair protein, S5 domain 2-like High mobility group box domain High mobility group box domain superfamily Histidine kinase/HSP90-like ATPase superfamily Ribosomal protein S5 domain 2-type fold Ribosomal protein S5 domain 2-type fold, subgroup
UniProtKB:B0S640 896
UniProtKB:Q8JFW5 194
UniProtKB:Q8AW22 39
UniProtKB:Q8JFR9 896
UniProtKB:A0A2R8RZA4 878
UniProtKB:Q1ED08 651
UniProtKB:Q7SXD5 372
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations