ZFIN ID: ZDB-GENE-030616-499
Gene Name: lysophosphatidic acid receptor 1
Gene Symbol: lpar1    Nomenclature History

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Previous Names: lpa1 (1), zlpa1 (1), edg2 (1), si:dz22b13.1, si:dz46m7.1, zgc:92157

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 10 Mapping Details/Browsers
Description: Exhibits lysophosphatidic acid receptor activity. Involved in cartilage development; hemangioblast cell differentiation; and vasculature development. Predicted to localize to cytoplasm and plasma membrane. Is expressed in several structures, including cardiovascular system; mesoderm; musculature system; nervous system; and pleuroperitoneal region. Orthologous to human LPAR1 (lysophosphatidic acid receptor 1).
Genome Resources: Alliance (1),  Gene:368461 (1),  Ensembl(GRCz11):ENSDARG00000099840 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
lpar1_unrecovered Point Mutation Unknown Unknown ENU
sa38782 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • vu374 Point Mutation Exon 2 Premature Stop ENU
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-lpar1 N/A 5
    MO2-lpar1 N/A 1
    MO3-lpar1 N/A 1
    DISEASE ASSOCIATED WITH lpar1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH lpar1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process angiogenesis (more)
    Cellular Component integral component of membrane (more)
    Molecular Function lysophosphatidic acid receptor activity (more)
    GO Terms (all 20)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA lpar1-201 (1)    Ensembl 1427
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM lpar1 No data available
    MARKER RELATIONSHIPS
    lpar1 Contained in: [BAC] DKEY-191B13 (1) (order this)
    [PAC] BUSM1-22B13, BUSM1-46M7 (1)
    lpar1 Encodes: [EST] eu103 (1)
    [cDNA] MGC:92157 (1), MGC:113901 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001004502 (1) 1693 nt
    Genomic GenBank:AL603747 (1) 93867 nt
    Select Tool
    Polypeptide UniProtKB:Q6DHQ8 (1) 346 aa
    Sequence Information (all 24)
    ORTHOLOGY for lpar1 ( Chr: 10 )
    CITATIONS (32)