Gene

ppargc1b

ID
ZDB-GENE-030616-43
Name
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
Symbol
ppargc1b Nomenclature History
Previous Names
  • perc1b (1)
  • fb55c08
  • sb:cb520
  • si:bz1d10.4
  • wu:fb55c08
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to enable nuclear receptor coactivator activity. Predicted to be involved in positive regulation of DNA-binding transcription factor activity and positive regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in cardiovascular system; cranial ganglion; immature eye; retina; and somite. Human ortholog(s) of this gene implicated in obesity. Orthologous to human PPARGC1B (PPARG coactivator 1 beta).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Northam et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ppargc1b Human Ortholog
No data available
Associated With ppargc1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000504 RNA recognition motif domain
Family IPR034605 PGC-1
Family IPR034621 Peroxisome proliferator-activated receptor gamma coactivator 1-beta
Homologous_superfamily IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily IPR035979 RNA-binding domain superfamily
Domain Details Per Protein
Protein Length Nucleotide-binding alpha-beta plait domain superfamily Peroxisome proliferator-activated receptor gamma coactivator 1-beta PGC-1 RNA-binding domain superfamily RNA recognition motif domain
UniProtKB:A0A2R8RN05 786
UniProtKB:A0A0R4IGS9 847
UniProtKB:B1A9X5 155
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations