ZFIN ID: ZDB-GENE-030616-413
Gene Name: titin, tandem duplicate 1
Gene Symbol: ttn.1
Sequence Ontology ID : SO:0000704

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Previous Names: TTN1 (1), ttnb, ttnl, hm:zeh1256r, im:6911926, si:dZ167C3.1, si:dz249n21.1, wu:fc09a12

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(Including Attributions)
Location: Chr: 9 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 74 figures from 6 publications
Directly Submitted Expression Data: 6 figures (7 images) from Thisse et al., 2004 [IMAGE:6911926]
  6 figures (9 images) from Thisse et al., 2004 [IMAGE:7137241]
  7 figures (13 images) from Thisse et al., 2004 [IMAGE:7152005]
  7 figures (19 images) from Thisse et al., 2005 [eu247]
  7 figures (15 images) from Thisse et al., 2004 [IMAGE:7148021]
  7 figures (17 images) from Thisse et al., 2004 [IMAGE:7158196]
  6 figures (17 images) from Thisse et al., 2004 [IMAGE:7155830]
  7 figures (16 images) from Thisse et al., 2004 [IMAGE:7158960]
  7 figures (18 images) from Thisse et al., 2004 [IMAGE:7159792]
  6 figures (13 images) from Thisse et al., 2004 [IMAGE:7163675]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hu7916 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa529 Point Mutation Unknown Premature Stop ENU
    sa656 Point Mutation Unknown Premature Stop ENU
    sa2520 Point Mutation Unknown Premature Stop ENU
    sa2521 Point Mutation Unknown Premature Stop ENU
    sa7209 Point Mutation Unknown Premature Stop ENU
    sa7211 Point Mutation Unknown Premature Stop ENU
    sa8651 Point Mutation Unknown Premature Stop ENU
    sa8738 Point Mutation Unknown Premature Stop ENU
    sa8776 Point Mutation Unknown Premature Stop ENU
    sa8875 Point Mutation Unknown Premature Stop ENU
    sa9015 Point Mutation Unknown Premature Stop ENU
    sa10165 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa10177 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa10376 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa10627 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa10628 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa11847 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa13738 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa14252 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa14401 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa14453 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa14924 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa15669 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa15731 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16133 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16157 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16201 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16349 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16491 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16757 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16841 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa17186 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa17611 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa18121 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa18130 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa18248 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa18518 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa18663 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21558 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21559 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21560 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21561 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21562 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21563 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21564 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21565 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21566 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21567 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21568 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21569 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21570 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa25435 Point Mutation Unknown Premature Stop ENU
    sa25436 Point Mutation Unknown Premature Stop ENU
    sa27455 Point Mutation Unknown Premature Stop ENU
    sa30923 Point Mutation Unknown Premature Stop ENU
    sa31742 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa31743 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa31744 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34726 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34727 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34728 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34729 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34730 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34731 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34732 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34733 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34734 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34735 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34736 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34737 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34738 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34739 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa38756 Point Mutation Unknown Premature Stop ENU
    sa38757 Point Mutation Unknown Premature Stop ENU
    sa38758 Point Mutation Unknown Premature Stop ENU
    sa41509 Point Mutation Unknown Premature Stop ENU
    sa41510 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41511 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41512 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41513 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41514 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41515 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41516 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41517 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41518 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41519 Point Mutation Unknown Splice Site ENU
    sa41520 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41521 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41522 Point Mutation Unknown Premature Stop ENU
    sa41523 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa45370 Point Mutation Unknown Premature Stop ENU
    sa45371 Point Mutation Unknown Premature Stop ENU
    sa45372 Point Mutation Unknown Premature Stop ENU
    xu066 Small Deletion Exon 5 Frameshift, Premature Stop TALEN
    xu067 Small Deletion Exon 177 Premature Stop TALEN
    xu069 Complex Unknown Unknown TALEN
    xu070 Complex Unknown Unknown TALEN
    xu071 Complex Unknown Unknown TALEN
    Targeting reagents:
    PHENOTYPE
    Data: 9 figures from 3 publications
    Observed in:
    DISEASE ASSOCIATED WITH ttn.1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    autosomal recessive limb-girdle muscular dystrophy type 2J Muscular dystrophy, limb-girdle, autosomal recessive 10 608807
    dilated cardiomyopathy 1G Cardiomyopathy, dilated, 1G 604145
    hypertrophic cardiomyopathy 9 Cardiomyopathy, familial hypertrophic, 9 613765
    tibial muscular dystrophy Tibial muscular dystrophy, tardive 600334
    Salih myopathy 611705
    Salih myopathy 611705
    Myopathy, proximal, with early respiratory muscle involvement 603689
    DISEASE ASSOCIATED WITH ttn.1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process myofibril assembly (more)
    Cellular Component M band (more)
    Molecular Function ATP binding (more)
    GO Terms (all 18)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000719 (1)
  • InterPro:IPR003598 (1)
  • InterPro:IPR003599 (1)
  • InterPro:IPR003961 (1)
  • InterPro:IPR007110 (1)
  • InterPro:IPR008266 (1)
  • InterPro:IPR011009 (1)
  • InterPro:IPR013098 (1)
  • InterPro:IPR013783 (1)
  • InterPro:IPR036116 (1)
  • InterPro:IPR036179 (1)
  • PROSITE:PS00109 (1)
  • PROSITE:PS50011 (1)
  • PROSITE:PS50835 (1)
  • PROSITE:PS50853 (1)
  • Pfam:PF00041 (1)
  • Pfam:PF00069 (1)
  • Pfam:PF07679 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ottdart00000004032 (1) 2267
    ttn.1-001 (1) 88553
    Select Tool
    ttn.1-002 (1) 67081
    Select Tool
    ttn.1-003 (1) 16776
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM ttn.1 No data available
    MARKER RELATIONSHIPS
    ttn.1Contained in: [BAC] CH211-198B21 (1) (order this), DKEY-190I10 (1) (order this)
    [PAC] BUSM1-167C3 (1) (order this), BUSM1-249N21 (1) (order this)
    ttn.1Encodes: [EST] eu247 (1), fc09a12 (1), fz71a10, IMAGE:6911926 (1) (order this), IMAGE:7137241 (1) (order this), IMAGE:7148021 (1) (order this), IMAGE:7152005 (1) (order this), IMAGE:7155830 (1) (order this), IMAGE:7158196 (1) (order this), IMAGE:7158960 (1) (order this), IMAGE:7159792 (1) (order this), IMAGE:7163675 (1) (order this), fc09b12 (1), fc52g09 (1), zeh1256r
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA WashUZ:wz12773 898bp
    Genomic GenBank:DQ649453 (1) 441087bp Blast at MegaBLAST
    Polypeptide UniProtKB:G1K2X0 (1) 29152aa
    Sequence Information (all 31)
    OTHER ttn.1 GENE PAGES
  • Alliance (1)
  • VEGA:OTTDARG00000003844 (1)
  • VEGA:OTTDARG00000026198 (1)
  • Ensembl(GRCz11):ENSDARG00000000563 (1)
  • ORTHOLOGY for ttn.1 (Chr: 9)
    CITATIONS (31)