ZFIN ID: ZDB-GENE-030616-37
Gene Name: N-ethylmaleimide-sensitive factor a
Gene Symbol: nsfa    Nomenclature History

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Previous Names: nsf, si:bz18k17.1, wu:fj33g11

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to have ATPase activity. Involved in animal organ development; neurogenesis; and pigment granule localization. Predicted to localize to Golgi stack. Is expressed in several structures, including nervous system; neural rod; neural tube; swim bladder; and trigeminal placode. Orthologous to human NSF (N-ethylmaleimide sensitive factor, vesicle fusing ATPase).
Genome Resources: Alliance (1),  Gene:368483 (1),  Ensembl(GRCz11):ENSDARG00000007654 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
s364 Unknown Unknown Unknown ENU
sa33226 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa33227 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44566 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • st25 Point Mutation Unknown Missense ENU
    st53 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • tpl6Gt Transgenic Insertion Unknown Unknown DNA
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-nsfa N/A 2
    DISEASE ASSOCIATED WITH nsfa HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH nsfa VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process afferent axon development in posterior lateral line nerve (more)
    Cellular Component Golgi stack (more)
    Molecular Function ATPase activity (more)
    GO Terms (all 19)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA nsfa-201 (1)    Ensembl 3184
    ncRNA nsfa-002 (1)    Ensembl 937
    nsfa-003 (1)    Ensembl 819
    ottdart00000049838 (1) 819
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM nsfa
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg(-6.5myo6b:nsfa-EGFP) myo6b EGFPnsfa Danio rerio 2 3
    Tg(neurod1:nsfa-EGFP) neurod1 EGFPnsfa Danio rerio 1 3
    MARKER RELATIONSHIPS
    nsfa Contained in: [BAC] RP71-18K17 (1)
    nsfa Encodes: [EST] fj33g11, IMAGE:7149165 (1)
    [cDNA] MGC:56054 (1), MGC:192747 (1), MGC:198197 (1), MGC:198446 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001044328 (1) 3186 nt
    Genomic GenBank:AL590145 (1) 135675 nt
    Select Tool
    Polypeptide UniProtKB:B7ZV62 (1) 744 aa
    Sequence Information (all 29)
    ORTHOLOGY for nsfa ( Chr: 3 )
    CITATIONS (48)