ZFIN ID: ZDB-GENE-030616-262
Gene Name: isovaleryl-CoA dehydrogenase
Gene Symbol: ivd    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: sb:cb425, si:dz181p14.1, wu:fb34d07

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 17 Mapping Details/Browsers
Description: Predicted to have isovaleryl-CoA dehydrogenase activity. Predicted to be involved in oxidation-reduction process. Predicted to localize to mitochondrion. Is expressed in alar plate midbrain region; digestive system; immature eye; musculature system; and optic tectum. Human ortholog(s) of this gene implicated in amino acid metabolic disorder and isovaleric acidemia. Orthologous to human IVD (isovaleryl-CoA dehydrogenase).
Genome Resources: Alliance (1),  Gene:368775 (1),  Ensembl(GRCz11):ENSDARG00000042853 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6485 Point Mutation Unknown Splice Site ENU
sa23118 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH ivd HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    isovaleric acidemia Alliance Isovaleric acidemia 243500
    DISEASE ASSOCIATED WITH ivd VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process oxidation-reduction process (more)
    Molecular Function acyl-CoA dehydrogenase activity (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ivd-201 (1)    Ensembl 2140
    ivd-203 (1)    Ensembl 553
    ncRNA ivd-003 (1)    Ensembl 752
    ivd-004 (1)    Ensembl 575
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ivd No data available
    MARKER RELATIONSHIPS
    ivd Contained in: [BAC] CH211-210H14 (1)
    [PAC] BUSM1-181P14 (1)
    ivd Contains: [SNP] rs3728872 (1), rs3728873 (1), rs3728874 (1)
    ivd Encodes: [EST] cb425 (order this), fb34d07, IMAGE:7136352 (1)
    [cDNA] MGC:55688 (1), MGC:86783 (1), MGC:191695 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_201491 (1) 2119 nt
    Genomic GenBank:BX649281 (1) 157279 nt
    Select Tool
    Polypeptide UniProtKB:Q7ZTH9 (1) 418 aa
    Sequence Information (all 26)
    ORTHOLOGY for ivd ( Chr: 17 )
    CITATIONS (24)