Gene

itsn1

ID
ZDB-GENE-030616-226
Name
intersectin 1 (SH3 domain protein)
Symbol
itsn1 Nomenclature History
Previous Names
  • si:dz173a8.1
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to have calcium ion binding activity and guanyl-nucleotide exchange factor activity. Predicted to be involved in intracellular signal transduction. Orthologous to human ITSN1 (intersectin 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Dergai et al., 2010
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With itsn1 Human Ortholog
No data available
Associated With itsn1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR018247 EF-Hand 1, calcium-binding site
Conserved_site IPR001331 Guanine-nucleotide dissociation stimulator, CDC24, conserved site
Domain IPR000008 C2 domain
Domain IPR000219 Dbl homology (DH) domain
Domain IPR000261 EH domain
Domain IPR001452 SH3 domain
Domain IPR001849 Pleckstrin homology domain
Domain IPR002048 EF-hand domain
Homologous_superfamily IPR011992 EF-hand domain pair
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR035892 C2 domain superfamily
Homologous_superfamily IPR035899 Dbl homology (DH) domain superfamily
Homologous_superfamily IPR036028 SH3-like domain superfamily
Domain Details Per Protein
Protein Length C2 domain C2 domain superfamily Dbl homology (DH) domain Dbl homology (DH) domain superfamily EF-Hand 1, calcium-binding site EF-hand domain EF-hand domain pair EH domain Guanine-nucleotide dissociation stimulator, CDC24, conserved site PH-like domain superfamily Pleckstrin homology domain SH3 domain SH3-like domain superfamily
UniProtKB:A0A0R4IWJ1 1720
UniProtKB:Q7ZZ79 203
UniProtKB:A8E7E7 1722
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations