ZFIN ID: ZDB-GENE-030616-226
Gene Name: intersectin 1 (SH3 domain protein)
Gene Symbol: itsn1    Nomenclature History

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Previous Name: si:dz173a8.1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to have molecular adaptor activity. Predicted to be involved in clathrin-dependent synaptic vesicle endocytosis. Predicted to localize to several cellular components, including clathrin-coated pit; intracellular vesicle; and presynaptic membrane. Orthologous to human ITSN1 (intersectin 1).
Genome Resources: Alliance (1),  Ensembl(GRCz11):ENSDARG00000000086 (2)
GENE EXPRESSION No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH itsn1 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH itsn1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process intracellular signal transduction (more)
Cellular Component clathrin-coated pit (more)
Molecular Function calcium ion binding (more)
GO Terms (all 8)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA itsn1-002 (1) 4622
itsn1-201 (1)    Ensembl 5681
ottdart00000003965 (1) 5197
ncRNA itsn1-003 (1) 644
ottdart00000009539 (1)    Ensembl 3923
Browsers: EnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM itsn1 No data available
MARKER RELATIONSHIPS
itsn1 Contained in: [BAC] CH211-287J19 (1), DKEY-22N8 (1) (order this)
[PAC] BUSM1-69G10 (1), BUSM1-173A8 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA GenBank:AL915730 (1) 539 nt
Genomic GenBank:BX005416 (1) 163197 nt
Select Tool
Polypeptide UniProtKB:A8E7E7 (1) 1722 aa
Sequence Information (all 9)
ORTHOLOGY for itsn1 ( Chr: 1 )
CITATIONS (23)