Gene

map4k2

ID
ZDB-GENE-030616-163
Name
mitogen-activated protein kinase kinase kinase kinase 2
Symbol
map4k2 Nomenclature History
Previous Names
  • map4k2l
  • si:dz150l22.2
  • si:dz263j20.1
  • zgc:136670
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have MAP kinase kinase kinase kinase activity. Predicted to be involved in several processes, including activation of protein kinase activity; signal transduction by protein phosphorylation; and stress-activated protein kinase signaling cascade. Predicted to localize to cytoplasm. Orthologous to human MAP4K2 (mitogen-activated protein kinase kinase kinase kinase 2).
Genome Resources
Note
None
Expression
All Expression Data
Fig. 4 from Nguyen et al., 2011
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With map4k2 Human Ortholog
No data available
Associated With map4k2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000719 Protein kinase domain
Domain IPR001180 Citron homology (CNH) domain
Family IPR021160 Mitogen-activated protein (MAP) kinase kinase kinase kinase
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Domain Details Per Protein
Protein Length Citron homology (CNH) domain Mitogen-activated protein (MAP) kinase kinase kinase kinase Protein kinase, ATP binding site Protein kinase domain Protein kinase-like domain superfamily
UniProtKB:Q8UV58 407
UniProtKB:A0A1D5NSJ2 195
UniProtKB:Q7ZZ99 632
UniProtKB:Q7ZZ66 675
UniProtKB:Q1RLZ2 865
UniProtKB:Q5VSN5 811
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations